204 SELECTED ARTICLES. 
Summary comparison between the three numbers. 
Pain experienced. 
Serosity at the raising of 
the blister. 
Condition of blis- 
tei"ed surface. 
Time of drying. 
No. 1 — Time of ap- 
plication, six hours. 
The pains felt were 
itching, prickings and 
heat. 
These effects were 
very prompt upon 5 
patients, who could 
reply satisfactorily. 
A-bout 2 spoonsful 
of serous matter, lim- 
pid and of a citron 
yellow colour. 
Blister always well 
formed, except upon 
one patient, which 
broke during the 
night. 
Simple red- 
ness of skin. 
Desiccated al- 
most always 
the sixth day. 
No. 2. — Time six 
hours. 
The pains felt were 
prickings, smarting, 
and heat, which upon 
almost all the patients 
remained until the 
morning of the next 
day. 
A spoonful and a 
half of serum. 
Blister well formed 
except upon one pa- 
tient. 
Skin slightly 
coloured red. 
Desiccation 
obtained the 
sixth day. 
No. 3. —Time four 
hours. 
Pains less sensible, 
and consist in prick- 
ings, itchings, and 
smarting. 
Two spoonsful of 
serum and rupture of 
vesicle upon one pa- 
tient. 
Skin colour- 
ed rose red. 
Desiccation 
obtained the 
fifth day. 
Medical experience has given the advantage to No. 3; the 
blister is the quickest made, the pain less severe and of short- 
er duration, and the healing more prompt. These advantages 
are evidently owing to the absence of the euphorbium, whose 
persistant acridity is joined without any benefit to the more 
mild vesicating property of the cantharides. We are thus 
brought to give the preference to Henry & Guibourt's formu- 
la, although the product has not that appearance we are accus- 
tomed to find in the vesicarting taflfetas commonly employed. 
This preparation presents a phenomenon somewhat remark- 
able; which is that the cantharadine often separates in crys- 
tals from the middle of the mass^ which is likewise filled 
with a multitude of small white needles. 
No doubt this preparation loses by contact with the air. It 
