180 
Original Communications. 
and Dr. Kollock, of Georgia, uses the following language 
with regard to it: "It is a vermifuge of efficacy. Its use 
is in some measure general among the planters, and with 
many supercedes the use of all others. I have given it with 
success, where all others in common use have failed of reliev- 
ing. But when given in the months of March and April, 
while the sap is mounting into the tree, it has sometimes been 
followed by stupor, dilatation of the pupil, stertorous breath- 
ing, &c. But these symptoms, like those sometimes produced 
by Spigelia, pass off without any perceptible injury to the 
system." This article he goes on to state is also applicable 
in the same manner as the pink root to those febrile affec- 
tions of children, resembling the irritative fever often accom- 
panying the presence of worms. 
Dr. Duvall also gives much corroborative testimony in sup- 
port of the efficacy of this remedy, not only in cases of Lum- 
brici, but also where Taeniae are present. In Cochin China, 
according to Ainslie, {Mat Ind.. ii. 455,) it is well known to 
the native practitioners, by the name of din, oots or sedan, 
and used as an anthelmintic, but is administered with great 
caution; quia nimia dosi vertigeriem et convulsiones affert. 
(Louriero ; Flor. Coch. China, i. 269.) 
The leaves are likewise endowed with some activity; in the 
Diet Univer. des Plantes it is stated that a decoction of them 
is eminently purgative, but this does not appear to be support- 
ed by the experiments of Dr. Duvall, added to which horses 
and cattle feed on them, with perfect impunity ; in all proba- 
bility, they will be found very analogous to those of the M. 
azadirachta, which are astringent and tonic. Dr. Skipton of 
Calcutta, has used the latter with the happiest success in hys- 
teria, {Trans. Med. Phys. Soc. Calcutta, i. 123.) 
The berries, which are sweetish, are said by Dr. Kollock 
to be anthelmintic, though only in large doses ; in some cases, 
however, they cause unpleasant effects; thus M. Tournon 
gives a case in which convulsions and the most copious vom- 
iting and purging were produced by the ingestion of two or 
three of them. {Journ. Gen. de Med. xlviii. 25.) They fur* 
