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Selected -Articles. 
much diversity of effect when employed in large or medium 
doses with young subjects. 
Cases requiring the tincture, differ from those already no- 
ticed, chiefly on account of the more strongly marked de- 
velopements,with which they are associated; in such examples 
of epilepsy, a decided hydropic diathesis not unfrequently ob- 
tains; the adipose textures generally, but more especially of 
the skin, are disposed to bloat a little, with universal pallidness 
and reduced temperature ; the secretions from the skin, bow- 
els and kidneys, are generally defective ; the pulse is occa- 
sionally slow, feeble, and soft, but more frequently it is pre- 
ternaturally active and corded, from the nervous mobility 
generally attendant upon imperfect sanguification ; such pa- 
tients are nearly always languid and sluggish, and often re- 
quire diffusible stimuli to rouse the enfeebled energies, both of 
body and mind, to something like a comfortable state of exci- 
tation : with such subjects the approach of the paroxysm is 
more gradual, and may, in many instances, be foreseen for 
hours, and sometimes days. To this complication of epilepsy, 
the tincture is most happily adapted, as it presents the remedy 
in the form best calculated to act promptly, as well as to meet 
the several indications of cure. It should, (as advised with 
regard to the crust in substance,) always be commenced with 
at night, and in the minimum doses ; from ^ss. to jiss. may 
be given, properly diluted, three or four times during the day. 
Being less permanent in its effects, the tincture should be 
given more frequently than the crust in substance, especially 
if the symptoms are urgent; these doses may be repeated 
with safety as often as once in three or four hours. 
Occasionally in this form or complication of epilepsy, it 
becomes necessary to employ tonics, either mineral or vege- 
table, or perhaps both, before the tincture, (or powder,) can 
be given with the least benefit. By invigorating the organic 
tone, upon which the normal functional actions materially 
depend, (especially of the digesto-nutritive systems,) our 
agent is enabled the more effectually to produce its specific 
remediate excitation. That debility exists in these cases, may 
be inferred from the general anaemial aspect of such patients. 
