Am.  Jour.  Pharm.  \ 
January,  1908.  J 
Approved  Proprietary  Preparations. 
29 
acid.  Guajasanol  has  been  recommended  for  the  treatment  of 
tuberculosis,  both  internally  and  subcutaneously.  It  is  also  recom- 
mended as  a  deodorant  and  is  said  to  have  given  good  service  in 
putrid  cystitis.  Dosage. —  I  to  3  grammes  (15  to  45  grains)  in 
wafers  ;  subcutaneously,  3  to  4  grammes  (45  to  60  grains)  in  20  per 
cent,  aqueous  solution  ;  locally  it  may  be  used  in  from  o-i  to  2  per 
cent  solutions.  Manufactured  by  Farbwerke,  vorm.  Meister,  Lucius 
&  Bruening,  Hoechst  a.  M.  (Victor  Koechl  &  Co.,  New  York). 
U.  S.  patent  No.  624,722. 
HEDONAL. — METHYLPROPYLCARBINOL  URETHANE.  PENTAN-2-OL- 
URETHANE. 
Hedonal,  CH3.CH2.CH2.CH(CH3)  O.CO.NH2  =  C6H1302N,  is  a 
urethane  differing  from  ethyl  carbamate,  U.S.P.,  in  that  the  ethyl 
radicle  has  been  replaced  by  the  radicle  of  methylpropylcarbinol 
(pentan-2-ol).  CH3.CH2.CH2.CHOH.CH3. 
Actions  and  Uses.— Hedonal  appears  to  have  a  greater  hypnotic 
effect  than  ethyl  carbamate.  It  is  said  to  be  followed  by  no  after- 
effects and  is  oxidized  in  the  body  to  urea  and  carbon  dioxide.  It 
is  recommended  in  insomnia  due  to  mental  overwork  or  nervous 
excitement  occurring  in  the  course  of  neurasthenia  or  hysteria.  It 
is  claimed  to  be  particularly  useful  preliminary  to  anesthesia,  a  hyp- 
notic dose  being  given  and  anesthesia  effected  with  chloroform  after 
the  patient  has  been  asleep  for  an  hour.  Dosage. —  1  to  2  grammes 
(15  to  30  grains),  administered  dry,  followed  by  a  swallow  of  water, 
or  in  wafers  or  capsules.  Manufactured  by  Farbenfabriken,  vorm. 
Friedr.  Bayer  &  Co.,  Elberfeld,  Germany  (Continental  Color  and 
Chemical  Co.,  New  York).  U.  S.  patent  No.  659,202  ;  German 
patents  Nos.  11,496,  120,863,  120,864,  120,865. 
HELMITOL. 
A  name  applied  to  Hexamethylenamine  Methylencitrate  (which 
see). 
Manufactured  by  Farbenfabriken,  vorm.  Friedr.  Bayer  &  Co., 
Elberfeld,  Germany  (Continental  Color  and  Chemical  Co.,  New  York). 
U.  S.  patent.    U.  S.  trade-mark  No.  39,580. 
HEROIN.  DIACETYL- MORPHINE. 
Heroin,  C17Hl7(C2H302)2NO  =  C21H2305N,  is  a  synthetic  alkaloid 
obtained  by  the  acetylization  of  morphine. 
