294  Progress  in  Pharmacy.  {xm'£™e,ima,Tm' 
Camphosal  may  be  given  in  doses  of  from  5  to  15  minims.  (Chem. 
and  Drug.,  1908,  page  328.) 
Dimenthyldimethylene  ether  is  used  as  an  antiseptic  and  antipyretic. 
It  is  obtained  by  treating  menthol  with  symmetrical  di-halogen 
methyl  ether.    (Client,  and  Drug.,  1908,  page  328.) 
Ethyl  B or 0 salicylate  (Boryt)  — This  is  obtained  by  heating  together 
boric  acid,  62;  salicylic  acid,  138;  water,  about  200;  then  adding 
to  the  solution,  alcohol  (95  per  cent.)  60;  sulphuric  acid,  about  40; 
and  boiling  (under  a  reflux  condenser).  When  esterification  is  com- 
plete, and  after  washing  with  water  to  remove  the  sulphuric  acid, 
the  resulting  product  should  occur  in  crystalline  needles  having  a 
higher  melting  point  than  that  of  salicylic  acid. 
Ethyl  boro salicylate  has  been  recommended  for  use  externally  and 
internally  as  an  antiseptic  and  for  the  treatment  of  rheumatism. 
(Phar.  Jour.,  April  18,  1908,  page  518,  from  V  Union  Phar in) 
Iodofan. — F.  Zernik,  in  a  recent  address  to  the  German  Pharma- 
ceutical Society,  reiterates  his  former  statement  that  iodofan  con- 
tains only  4  per  cent,  of  iodine  instead  of  from  42  to  47  per  cent,  as 
claimed  by  the  manufacturers.  {Jour.  A.  M.  A.,  April  4,  1908, 
page  1135.) 
Neoform. — This  is  said  to  be  a  basic  tri-iodo-phenolate  of  bismuth, 
and  occurs  as  a  yellow  powder,  with  a  distinctive,  though  not  objec- 
tionable odor.  This  preparation  is  said  to  be  insoluble  in  the  ordi- 
nary solvents  and  does  not  melt  on  heating.  It  begins  to  decompose 
at  temperatures  varying  from  1700  to  1800. 
Neoform  is  said  to  be  useful  as  an  antiseptic  and  absorbent  powder. 
(Zeitschr.  d.  Allgemein.  Oest.  Apoth.  Ver.,  1908,  page  213.) 
Pyrenol. — H.  Thorns  reiterates  the  report  made  by  F.  Zernik, 
some  time  ago,  that  pyrenol  is  a  mechanical  mixture  composed  of 
equal  parts  of  sodium  salicylate  and  sodium  benzoate,  with  1  per 
cent,  of  benzoic  acid  and  a  trace  of  thymol,  not  more  than  0  3  per 
cent. 
The  product  is  evidently  obtained  by  fusing  a  mixture  of  the 
constituents.    (Apothek.  ZeiVg,  1908,  page  317.) 
Salol-Chloral — It  is  claimed  that  a  definite  compound  of  salol  and 
chloral  results  from  the  heating  together  on  a  water  bath,  at  about 
100°  C,  of  214  parts  of  salol  and  147  5  parts  of  hydrated  chloral. 
The  resulting  product  is  an  oily  liquid,  insoluble  in  water,  that  crys- 
tallizes on  cooling.    Salol  chloral  has  been  recommended  as  a  hyp- 
