Amjuivrifos.arm-}     Notes  on  "Physiological  Testing"  321 
LITERATURE  CITED. 
1  George  Watt  :  A  Dictionary  of  Economic  Products  of  India,  q,  Part  4,  p. 
358. 
2  Bentley  and  Tritnen  :  Medicinal  Plants,  4,  Monograph  270. 
3  Berg  und  Schmidt  :  Officinel  Gewachse,  Taf.  XXXIV,  b. 
*  Engler  und  Prantl  :  Die  natiirlichen  Pflanzenfamilien,  II.  Teil,  6.  Abteilung 
p.  26. 
5  F.  B.  Kilmer  :  American  Journal  of  Pharmacy,  ~o  (1898),  p.  75. 
6  P.  L.  Simmonds  :  Tropical  Agriculture,  p.  497. 
7  Arthur  Meyer  :  Wissenschaftliche  Drogenkunde,  Part  II,  p.  64. 
8  A.'Tschirch  und  O.  Oesterle  :  Anatomischer  Atlas,  Lief.  VI,  p.  109,  Taf  el 
XXVI. 
9  Joh.  Buchwald  :  Zeitschr.  J,  Untersuchung  d.  Nahr.-  u.  Genussmittel,  2 
(1899),  p.  947- 
10  R.  Reich  :  Zeitschr. /.  Untersuchung  d.  Nahr.-  u.  Genussmittel,  14  (1907), 
P-  549- 
11  A.  L.  Winton  and  W.  L.  Mitchell  :  Connecticut  Agricultural  Experiment 
Station,  Twenty-second  Annual  Report  (1898),  p.  144. 
12  E-  G.  Clayton:  The  Analyst,  34  (1899),  p.  122. 
NOTES  ON  "  PHYSIOLOGICAL  TESTING."1 
By  Albert  C.  Crawford, 
Bureau  of  Plant  Industry,  United  States  Department  of  Agriculture, 
Washington,  D.  C. 
I  was  asked  to  speak  on  the  question  of  physiological  testing,  I 
suppose,  because  of  my  former  connection  with  certain  of  the  large 
drug  firms.  This  connection  has  given  me  a  rather  closer  interest 
in  the  subject  than  is  usual  with  pharmacologists  in  this  country, 
and  I  had  planned  to  write  a  series  of  papers  on  these  methods. 
The  first  of  this  series — the  one  on  the  testing  of  suprarenal  glands 
— has  already  been  published,2  but  it  is  now  a  question  as  to  whether 
I  shall  be  able  to  complete  the  series. 
The  use  of  animals  for  testing  drugs  and  chemicals  is  a  method 
of  very  old  origin  and  long  antedates  the  use  of  the  term  "  physio 
1  Read  before  the  Baltimore  Branch  of  the  American  Pharmaceutical  Asso 
ciation,  May  21,  1908. 
2  Crawford,  A.  C.  Use  of  the  Suprarenal  Glands  in  the  Physiological  Test- 
ing of  Drug  Plants.  United  States  Department  of  Agriculture,  Bureau  of 
Plant  Industry,  Bulletin  112. 
