486  American  Pharmaceutical  Association.  {A™"cJ™er  Sis™' 
50  Cc.  was  taken  and  placed  in  a  250-Cc.  glass-stoppered  flask,  25 
Cc.  of  standard  bromine  solution  added,  and  the  mixture  acidulated 
with  5  Cc.  hydrochloric  acid  U.  S.  P. ;  the  mixture  was  shaken 
frequently  during  one-half  hour,  and  then  5  Cc.  potassium  iodide 
T.  S.  was  quickly  introduced  and  the  mixture  well  shaken.  The 
stopper  and  neck  of  the  flask  were  rinsed  with  water,  a  small 
amount  of  chloroform  added,  and  the  iodine  titrated  with  standard 
sodium  thiosulphate  V.  S. 
The  following  conclusions  are  drawn  from  these  experiments : 
First.  The  method  of  the  U.  S.  P.  for  the  valuation  of  phenol 
is  entirely  satisfactory,  and  also  may  be  applied  when  the  volume 
of  the  phenol  solution  is  as  great  as  50  Cc.  and  the  amount  of 
phenol  present  sufficient  to  absorb  from  10  to  90  per  cent,  of  the 
bromine  solution  added.  Second.  Phenol  can  be  completely  re- 
moved from  a  solution  containing  much  potassium  hydroxide  by  first 
saturating  with  carbon  dioxide  and  then  distilling  with  steam  in  a 
current  of  carbon  dioxide.  Third.  Under  these  conditions  as  much 
as  .150  Gm.  phenol  is  found  in  the  first  100  Cc.  distillate.  Fourth. 
The  presence  of  such  bodies  as  sulphites,  bromates,  and  nitrates 
does  not  affect  the  estimation  of  phenol  by  this  method. 
Solution  of  Chlorinated  Soda. 
By  H.  V.  Amy  and  O.  H.  Dawson. 
This  was  a  critique  of  the  process  of  manufacture  of  this  product 
as  given  by  U.  S.  P.  VIII,  showing  that  solutions  prepared  by  this 
process,  yielded  respectively,  2.01,  1.65  per  cent,  and  1.65  per  cent, 
available  Chlorine,  despite  the  fact  that  the  amount  of  chlorinated 
lime  used  was  increased  to  represent  the  pharmacopceial  content 
(30  per  cent.).  A  report  of  experiments  with  modifications  of  the 
process  of  the  Pharmacopoeia  of  1880,  by  which  the  chlorinated 
lime  paste  is  mixed  with  sodium  carbonate  solution  and  filtrate 
collected  was  given.  In  three  experiments,  12  Gm.  chlorinated 
lime  (26.7  per  cent.)  and  6.5  Gm.  monohydrated  sodium  carbonate 
were  used,  the  difference  in  methods  being  in  the  amount  of  water 
employed  and  consequently  the  amount  of  filtrate  obtained;  the 
quantities  of  filtrate  being  25  cc,  43  cc.  and  90  cc  respectively. 
In  the  fourth  experiment,  a  tenfold  recipe  was  used  and  900  cc 
filtrate  collected.  The  four  finished  solutions  assayed  respectively 
3.05  per  cent.,  2.50  per  cent.,  2.67  per  cent.,  and  2.85  per  cent, 
available  Chlorine. 
