53o 
Fluidgly  cerates. 
{ 
Am.  Jour.  Pharui 
November,  1908. 
readily  and  economically  prepare  and  not  be  dependent  upon  manu- 
facturers, as  they  can  be  prepared  even  more  easily  on  a  small 
scale  than  on  a  large  one.  Again  we  must  look  forward  to  the 
time  in  the  near  future,  when  the  druggists  will  be  compelled  to 
compound  remedies  of  potent  drugs  only  with  preparations  made 
within  recent  and  specified  time.  With  glycerin  replacing  alcohol, 
the  fiuidglycerates  would  be  an  economical  means  for  each  pharma- 
cist preparing  his  own  remedies  and  guaranteeing  them  and  renew- 
ing stock  frequently. 
The  writer  does  not  consider  fhat  his  experiments  covering  nearly 
ioo  drugs  have  in  all  cases  been  conclusive  and  in  the  detailed 
formulas  the  shortcomings  of  a  number  of  these  are  pointed  out. 
He  frankly  admits  that  numerous  experiments  are  necessary  to  prove 
the  stability  of  each  one  of  these  fiuidglycerates  and  also  that 
physiological  and  chemical  tests  should  be  applied  to  determine  the 
value  of  many  of  them.  He  hopes  that  some  one  will  thus  under- 
take to  prove  by  clinical  experiments  and  physiological  tests  the  value 
of  such  fiuidglycerates  as  those  of  Digitalis,  Ergot,  Gelsemium, 
Lobelia,  Pomegranate,  and  Veratrum.  The  work  so  far  done  on 
the  subject  is  only  preliminary,  but  it  appears  to  be  a  very  promising 
field  for  practical  pharmaceutical  experimentation. 
Dissolve  the  tartaric  acid  in  60  c.c.  of  the  glycerol- water  men- 
struum and  moisten  the  drug  with  the  solution  and  then  proceed  to 
percolate  and  finish  as  per  the  type  process. 
Very  little  sediment  has  formed  in  this  preparation.  It  has  re- 
mained entirely  clear  above  this  and  the  smallest  amount  gives  the 
characteristic  acrid  taste  and  tingling  sensation  of  aconite.  It 
mixes  clear  with  water,  syrup  or  diluted  alcohol,  but  becomes 
cloudy  with  alcohol.  It  assayed  by  the  U.  S.  P.  process  of  assaying 
Fluidextract  of  Aconite  0.435  Gm.  of  alkaloid  in  100  c.c.  The 
powdered  dry  marc  is  nearly  free  from  acridity  and  the  aconite 
was  practically  exhausted. 
Fluidglycerate  of  Aconite. 
Take  of  Aconite  Root,  in  number  20  powder 
Tartaric  Acid  
100  Gm. 
2  Gm. 
Fluidglycerate  of  Anthemis. 
Take  of  Anthemis  in  number  20  powder 
100  Gm. 
