Am.  Jour.  Pharm.  ) 
November,  1908.  j 
Fluidgly  cerates. 
535 
remained  clear,  with  only  the  faintest  trace  of  sediment.  It  is  rich 
in  color  and  taste  of  the  drug,  and  appears  well  worthy  of  medical 
consideration.  It  mixes  entirely  clear  with  water,  syrup,  or  diluted 
alcohol  but  with  alcohol  the  mixture  is  turbid. 
Fluidglycerate  of  Cinchona. 
Take  of  Cinchona  in  number  40  powder  100  Gm. 
Hydrochloric  Acid    5  c.c. 
Add  the  Hydrochloric  Acid  to  100  c.c.  of  the  glycerol-water  men- 
struum, and  in  this  mixture  rub  up  the  cinchona  to  a  paste ;  set 
this  aside  for  24  hours  to  macerate,  then  stir  up  thoroughly  and 
transfer  to  a  conical  glass  percolator.  Then  proceed  to  extract  and 
finish  in  accordance  with  the  type  process. 
The  product  is  a  thick  red  liquid,  which  while  slightly  cloudy,  has 
deposited  practically  no  sediment.  It  is  acid  and  very  bitter.  It 
mixed  clear  with  alcohol  or  diluted  alcohol,  and  with  syrup  prey 
duced  a  slight  cloudiness,  but  with  water  there  was  formed  a 
precipitate  of  the  bright  red  coloring  matter.  Assayed  by  the 
official  process  for  Assay  of  Fluidextract  of  Cinchona,  it  showed 
3.58  Gm.  anhydrous  ether-soluble  alkaloids  in  100  c.c. 
Fluidglycerate  of  Coca. 
Take  of  Coca  in  number  20  powder  100  Gm. 
Proceed  according  to  the  type  process,  using  100  c.c.  of  the 
glycerol-water  menstruum  to  moisten  the  drug. 
On  concentrating  the  percolate  there  was  produced  a  decided 
precipitate,  gritty  to  the  feel  and  taste.  This  was  isolated,  washed 
and  tested,  and  proved  to  be  calcium  oxalate.  The  strained  liquid 
has  remained  clear  and  has  a  decided  taste  and  odor  of  the  coca  leaf, 
and  this  is  brought  out  on  dilution.  It  mixes  clear  with  syrup  or 
diluted  alcohol  and  slightly  cloudy  with  water,  and  is  coagulated  by 
strong  alcohol.  Assayed  by  the  official  process  for  Assay  of  Fluid- 
extract  of  Coca,  it  showed  0.3  Gm.  ether-soluble  alkaloids  in  100  c.c. 
