392 
ON  TINCTURA  OPII  CAMPHORATA. 
Rub  the  powders  in  a  mortar  with  a  little  of  the  syrup  until 
perfectly  smooth,  and  then  add  the  remainder  and  mix  them. 
The  sedative  power  of  this  syrup  was  sometimes  increased  by 
adding  from  two  to  four  grains  of  cyanide  of  potassium  to  the 
whole  mixture,  in  which  case  the  cyanide  should  be  dissolved  in 
a  few  drops  of  water  and  added  to  the  mixture.  The  dose  is  a 
teaspoonful  three  or  four  times  a  day,  and  has  been  useful  in 
many  cases. 
ON  TINCTURA  OPII  CAMPHORATA. 
By  J.  C.  Wharton,  in  a  note  to  the  Editor. 
Bear  Sir, — I  send  you  a  formula  for  paregoric  which  can  be 
used  to  much  advantage,  and  is  in  my  judgment  perfectly  con- 
formable to  the  authority  of  the  U.  S.  Pharmacopoeia.  The 
preparation  of  this  tincture  by  this  formula  is,  in  regard  to  time, 
scarcely  more  than  a  matter  of  admixture  2ind  filtration.  A 
little  calculation  will  show  that  the  ingredients  and  proportions 
are  precisely  the  same  as  in  the  U.  S.  Pharmacopoeia,  save  that 
laudanum  is  substituted  for  opium  (an  allowance  being  made  for 
the  additional  diluted  alcohol).  The  magnesia  is  essential  to 
produce  a  clear  and  elegant  preparation. 
Yours,  truly,  J.  C.  Wharton. 
Nashville,  July  24,  1869. 
Tinetura  Opii  Camphorata,  U.  iS.  P, 
B  Laudanum,  6  fluidounces. 
Benzoic  Acid,  225  grains. 
Camphor,  in  fine  powder,  150  grains. 
Oil  of  Anise,  225  minims. 
Clarified  Honey,  7J  troyounces. 
Carbonate  of  Magnesia,  2  troyounces. 
Diluted  Alcohol,  a  sufficient  quantity. 
Eub  the  camphor,  oil  of  anise,  honey  and  magnesia  together 
well.    Then  add  by  degrees  seven  pints  and  two  fluidounces  of 
diluted  alcohol,  rubbing  in  a  mortar  till  a  uniform  mixture  is 
obtained.    Filter,  and  after  the  liquid  has  ceased  to  pass  add 
sufficient  diluted  alcohol  through  the  filter  to  displace  the  re- 
