INFLUENCE  OF  OIL  OF  SASSAFRAS  UPON  TOBACCO.  451 
green  tint,  in  ether  giving  a  magnificent  rose-purple,  and  in 
chloroform  with  a  fine  violet  tint. 
"  The  physiological  efi'ects  of  apomorphia  are  verj  difi*erent 
from  those  of  morphia  ;  a  very  small  dose  produces  speedy  vomit- 
ing and  considerable  depression,  but  this  soon  passes  off",  leaving 
no  after  ill  effects,—- facts  of  which  we  have  repeatedly  had  dis- 
agreeable proof  while  working  with  it." 
Dr.  Gee  is  now  studying  these  effects,  and  has  found  that 
j-^^th  of  a  grain  of  the  hydrochlorate  subcutaneously  injected,  or 
J  grain  taken  by  the  mouth,  produces  vomiting  in  from  four  to 
ten  minutes.  Our  friend  Mr.  Prus  allowed  himself  to  be  injected 
with  y^gth  grain,  which  produced  vomiting  in  less  than  ten 
minutes.  From  Dr.  Gee's  experiments  on  himself  and  others, 
he  concludes  that  the  hydrochlorate  is  a  non-irritant  emetic  and 
powerful  anti-stimulant.  As  from  these  properties  it  appears 
probable  that  it  may  come  into  use  in  medicine,  we  have  called 
it  apomorphia,  rather  than  morphinine,  to  avoid  any  possible 
mistakes  in  writing  prescriptions." — Land.  Pharm.  Journ.^  July^ 
1869. 
INFLUENCE  OF  OIL  OF  SASSAFRAS  UPON  TOBACCO. 
Editor  Boston  Journal  of  Chemistry  : 
The  interesting  article  in  the  May  number  of  the  Journal 
reminds  me  of  experiments  made  some  years  ago,  when  I  was  a 
smoker.  I  think  I  can  suggest  to  your  readers  a  more  agree- 
ble  antidote,  or  denicotizer,  than  the  tannic  acid. 
A  valuable  little  "  Treatise  on  Fever,"  by  Dezin  Thompson, 
Nashville,  Tenn.,  contains  the  following  statement : 
"  On  one  occasion,  while  waiting  upon  a  tedious  case  of  labor, 
I  amused  myself,  along  with  the  matrons  present,  in  the  enjoy- 
ment of  the  pipe  rather  freely,  and  suffered  a  good  deal  of  vertigo 
as  a  consequence.  In  the  course  of  the  conversation  which  the 
incident  gave  rise  to,  one  of  the  company  observed  that  the  dry 
bark  of  the  sassafras  combined  with  tobacco  would  prevent  its 
unpleasant  effects.  On  the  first  opportunity,  I  made  the  ex- 
periment, and  found  it  true  ;  the  sassafras  not  only  preventing 
the  injurious  effects  of  tobacco,  but  speedily  removing  them 
when  produced.    I  tested  this  repeatedly  by  smoking  in  a  strong 
