220 
Quinine  Salts. 
j  Am.  Jour.  Pharm. 
\      May,  1910. 
CODEINE  ALKALOID. 
The  solubility  of  this  alkaloid  in  ether  is  not  i  to  I2^>,  but  I 
to  25. 
CODEINE  PHOSPHATE. 
All  the  preparations  on  the  market  contain  only  y2  molecule  of 
water  of  crystallization.  The  salt  with  2  molecules  of  water  exists, 
but  it  is  a  practical  impossibility  to  produce  it  for  commercial 
purposes. 
The  salt  with  y2  molecule  of  water  ought  to  be  made  official, 
being  the  pure  commercial  chemical. 
DIACETYL  MORPHINE  HYDROCHLORIDE. 
In  all  the  publications  pertaining  to  this  salt  the  formula  is 
written  C17H17  (C2H30)2N03HC1,  this  having  reference  to  the 
anhydrous  salt,  which,  however,  cannot  be  made  commercially.  The 
salt,  when  freshly  prepared  from  an  alcoholic  solution  in  the  regular 
way  and  dried  in  the  air,  contains  3  molecules  of  water  of  crystal- 
lization. When  dried  at  a  moderate  heat  it  becomes  anhydrous, 
but  if  this  anhydrous  crystalline  powder  is  taken  from  the  drying- 
room  it  absorbs  quickly  1  molecule  of  water  of  crystallization  from 
the  air.  Therefore,  no  anhydrous  salt  can  be  found  on  the  market. 
The  following  formula  ought  to  be  adopted  for  this  chemical : 
C17H17(C2H30)2N0;!HC1  +  H20,  which  accordingly  contains 
95.75  per  cent,  of  anhydrous  salt  and  4.25  per  cent,  of  water  of 
crystallization,  and  which  is  the  pure  commercial  salt. 
STRYCHNINE  ALKALOID. 
Solubility  in  alcohol  at  25 0  C  1  :  150 
Solubility  in  chloroform  at  25 0  C  1:7 
STRYCHNINE  NITRATE. 
Solubility  in  water  at  25 0  C  1:55 
Solubility  in  alcohol   1  :  220 
STRYCHNINE  SULPHATE. 
Strychnine  sulphate  does  not  melt  at  2000  C.  If  heated  to  about 
2500  C.  it  begins  to  get  brown,  and  at  a  higher  temperature  it 
