4o8 
Assay  of  US. P.  Halogen  Compounds, 
Am.  Jour.  Pharm. 
September.  1910. 
alkaline  or  the  acid  boiling,  experiments  were  carried  out  in 
which  the  boiling  time  of  one  remained  constant  (one  hour),  while 
the  boiling  time  of  the  other  varied  (up  to  three  hours).  The 
results  obtained  are  given  in  the  accompanying  tables. 
TABLE  I 
Effect  of  Varying  the  Time  of  the  Acid  Boiling 
No.  of 
experiment 
Amount  of 
thymol  iodide 
Time  of 
alkaline 
boiling 
Time  of 
acid  boiling 
^AgN03 
required 
Apparent 
iodine 
content 
Gm. 
Min. 
Min. 
c.c. 
Percent. 
0.3 
60 
15 
10 . 62 
44-93 
o.3 
60 
30 
10.68 
45.18 
3  
o-3 
60 
45 
10  .  70 
45-27 
4  
0.3 
60 
60 
10.58 
44.76 
5  
o.3 
60 
120 
10  .  70 
45-27 
6  
6-3 
60 
180 
10 .  70 
45-27 
TABLE  II 
Effect  of  Varying  the  Time  of  the  Alkaline  Boiling 
No.  of 
experiment 
Amount  of 
thymol  iodide 
Time  of 
alkaline 
boiling 
Time  of 
acid  boiling 
^AgNOa 
required 
Apparent 
iodine 
content 
Gm. 
Min. 
Min. 
c.c. 
Percent. 
I 
o.3 
0 
60 
5-35 
22  .63 
2 
0.3 
15 
60 
10 . 00 
42.31 
3 
o.3 
3° 
60 
10.52 
44.  5 1 
4 
o.3 
45 
60 
10 . 70 
45.27 
5 
60 
60 
10.65 
45.06 
6 
2:5 
120 
60 
10.72 
45-35 
7 

0.3 
180 
60 
10.77 
45.56 
TABLE  III 
Effect  of  Varying  the  Amount  of  Thymol  Iodide 
Time  of  alkaline  boiling:  One  hour. 
Time  of  acid  boiling:  One  hour. 
No.  of  experiment 
Amount  of 
thymoljodide 
^AgNOs 
required 
Apparent 
iodine 
content 
Gm. 
c.c. 
Percent. 
  O.I 
3-57 
45.31 
  0.2 
7.15 
45-37 
10 . 60 
44.85 
14.35 
45-53 
17.87 
45.36 
Percentage  of  iodine  in  thymol  iodide,  according  to  U.S.P   45  .00 
Apparent  iodine  content  as  found  by  fusion  method  (similar  to  that 
of  Gane  and  Webster)   44  •  5 2 
