450 
Progress  in  Pharmacy. 
J  Am.  Jour.  Pharm. 
|  September,  1910. 
Pharmacopoeias  marked  +  ?  contain  only  a  general  article  on 
medicinal  wines,  but  no  tests  for  or  descriptions  of  wine  itself. 
Pharmacopoeias  marked  *  contain  a  general  descriptive  article 
on  wine  but  no  standards  for  any  particular  kind  of  wine. 
Antipyrin. — G.  O.  H.  Wallace  (Lancet)  records'  a  case  of 
acute  poisoning  by  10  grains  of  antipyrin.  Within  fifteen  minutes 
of  taking  the  drug  the  patient  complained  of  faintness  and  suffo- 
cation and  the  face  became  "  blotchy  "  and  swollen.  While  being 
examined  she  suddenly  collapsed  and  became  unconscious,  but  re- 
vived, and  after  treatment  in  bed  for  two  days  recovered.  The 
most  marked  features  of  the  case  were  the  rapid  onset  and  recovery, 
a  low  temperature,  and  great  prostration  {Pharm.  J.  Lond.,  1910, 
v.  85,  p.  130). 
Antityphoid  Vaccination. — Frederick  M.  Hartsock,  Major. 
Medical  Corps,  U.  S.  Army,  reports  the  results  of  1100  inoculations 
or  antityphoid  vaccinations  by  means  of  the  injection  of  dead 
typhoid  bacilli.  This,  he  asserts,  is  destined  to  be  a  practical  meas- 
ure of  prophylaxis  and  will  be  particularly  useful  in  the  handling 
of  typhoid  epidemics.  In  his  experience  no  untoward  results  were 
noted ;  all  patients  recovered  promptly.  Even  in  the  limited  number 
of  cases  (10)  in  which  the  reaction  was  severe  the  patients  were 
able  to  attend  to  duty  after  24  hours  (/.  Am.  M.  Ass.,  1910,  v.  54, 
p.  2123). 
Bismuth  Milks. — Dr.  Judson  A.  Hulse  warns  against  the  use 
of  bismuth  preparations  in  the  shape  of  creams,  milks,  etc. 
In  a  series  of  observations  covering  their  administration  to 
21  infants  suffering  from  acute  gastro-enteric  conditions,  he  failed 
to  observe  a  sedative  or  astringent  action  in  a  single  case.  In  a 
number  of  cases  the  bismuth  milk  passed  through  the  entire  ali- 
mentary tract  practically  unchanged,  while  in  control  observations 
it  was  found  that  the  administration  of  bismuth  subnitrate  resulted 
in  darkened  stools,  lessened  amount  of  blood,  and  almost  complete 
disappearance  of  mucus  within  the  first  twenty-four  hours  of  its 
administration  (/.  Am.  M.  Ass.,  1910,  v.  55,  p.  236). 
(To  be  continued. ) 
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