Am.  Jour.  Pharm.  ) 
^October,  1910.  J 
Oil  of  Sesamum. 
479 
which  I  have  experimented  for  a  number  of  years.  Specimens 
are  herewith  submitted  and  some  of  the  galenicals  will  be  prepared 
before  you  extemporaneously. 
LINIMENTUM  AMMONITE. 
Undoubtedly  all  of  you  are  familiar  with  the  shortcomings  of 
the  present  U.S. P.  formula  for  this  liniment,  which  are:  i.  Four 
ingredients  instead  of  two.  2.  The  cumbersome  method.  3.  The 
yellow  color.  4.  The  separation  into  layers.  5.  The  thinness 
when  freshly  prepared.    6.  The  thickening  by  age. 
It  is  certainly  impracticable  to  mix  four  ingredients  together 
when  five  cents'  worth  of  hartshorn  liniment  is  called  for,  the 
U.S. P.  stating:  "The  liniment  should  be  freshly  prepared  when 
wanted." 
Although  Eugene  Dieterich,  the  great  German  manufacturing 
pharmacist,  is  generally  credited  with  the  original  use  of  sesame 
oil  in  the  preparation  of  ammonia  liniment,  I  have  found  that  as 
early  as  1884,  F-  M.  Alcock  states  on  page  282  of  the  Pharmaceutical 
Journal  and  Transactions,  London:  "Sesame  oil  makes  a  more 
satisfactory  ammonia  liniment  than  olive  or  other  oils ; — even  after 
standing  three  (3)  months  there  is  no  sign  of  separation  and  the 
liniment  presents  a  beautiful  creamy  consistency  and  color  but 
slightly  altered  during  the  time  stated." 
From  experiments  during  a  period  of  several  years  I  have 
arrived  at  the  conclusion  that  as  per  demonstration  you  can  prepare 
an  ideal  ammonia  liniment  by  shaking  together :  sesame  oil,  3  parts 
by  weight,  and  ammonia  water,  1  part  by  weight. 
My  opinion  is  that  it  is  an  advantage,  being  easier  and  cleaner, 
to  weigh  the  ingredients  instead  of  measuring  them. 
This  liniment  has  the  following  advantages : 
1.  It  contains  only  2  ingredients. 
2.  It  can  be  prepared  quickly  and  easily. 
3.  The  resulting  liniment  is  snow-white. 
4.  It  is  homogeneous  and  does  not  separate  into  two  layers. 
5.  It  has  the  proper  creamy  consistency,  not  too  thick  and 
not  too  thin. 
6.  It  is  permanent  and  will  not  thicken  materially  by  age,  as 
you  can  convince  yourself  by  a  specimen  over  a  year  old. 
