484 
Progress  in  Pharmacy. 
("Am.  jour.  Phariii. 
\    October,  1910. 
Nuclein,  Nucleic  Acids,  and  Nucleates. — A  general  article 
describing  these  compounds  has  been  prepared  by  the  Council  on 
Pharmacy  and  Chemistry  for  publication  in  N.N.R. 
These  products  have  been  more  or  less  widely  used  but  their 
true  value  is  as  yet  undetermined  and  many  capable  observers  are 
inclined  to  think  that  the  claims  that  have  been  made  for  the 
therapeutic  value  of  these  compounds  are  not  based  on  sound  con- 
clusions (/.  Am.  M.  Ass.,  1910,  v.  55,  p.  503). 
Oil  of  Rose. — An  editorial  asserts  that  this  year  an  unusual 
variety  of  adulterants  have  been  put  in  the  stills  in  the  manufacture 
of  otto  of  rose  in  Bulgaria  and  cautions  the  buyers  to  be  on  their 
guard  (Chem.  and  Drug.,  London,  July  30,  1910,  p.  149). 
Podophyllum  resin  adulterated  with  aloes  is  reported  by 
Joseph  H.  Williams  who  found  approximately  25  per  cent,  of 
powdered  aloes  in  a  sample  of  resin  of  podophyllum  which  came 
within  the  limits  of  the  tests  prescribed  by  the  Ph.  Brit.  IV.  Williams 
thinks  it  would  be  advisable  to  apply  tests  for  water  soluble  material 
in  resin  of  podophyllum  (Pharm.  J.,  London,  1910,  v.  30,  p.  608). 
Pumpkin  Seed  as  a  Vermifuge. — H.  H.  Dale  reports  a 
pharmacologic  study  of  pumpkin  seed.  He  finds  that  neither  the 
expressed  oil  nor  the  resin  exert  any  anthelmintic  or  other  physi- 
ological action.  He  holds  that  any  value  that  the  seeds  may 
possess  when  administered  in  substance  must  be  attributed  solely 
to  mechanical  action. 
In  a  further  contribution  Power  and  Salway  report  that  they 
have  failed  to  find  any  alkaloid,  glucoside,  or  other  definite  com- 
pound likely  to  possess  therapeutic  action  (Pharm.  J.,  London. 
1910,  v.  30,  p.  703). 
Quinine  and  urea  hydrochloride  is  being  used  quite  widely 
as  a  local  anaesthetic.  In  a  recent  number  of  the  Journal  of  the 
American  Medical  Association  (June  11,  p.  1940),  W.  O.  Green 
reports  4  cases  in  which  the  substance  was  used  with  apparently 
satisfactory  results. 
Quinine  Arsenate. — The  Council  on  Pharmacy  and  Chemistry 
of  the  American  Medical  Association  reports  that  quinine  arsenate 
was  submitted  to  the  staff  of  clinical  consultants  and,  on  their 
recommendation,  refused  recognition  in  New  and  Non-official 
Remedies  because  it  does  not  appear  that  this  preparation  possesses 
any  properties  that  may  not  be  found  in  a  simple  mixture  of  its 
components.   Attempts  to  substitute  it  for  other  quinine  salts  would 
