SACCHARINE  CARBONATE  OF   IRON  AND  MANGANESE. 
127 
similar  manner  to  that  described  in  reference  to  the  purification 
of  crude  naphthaline  oil,  and  the  heavier  and  lighter  oils,  and  also 
the  denser  substances  extracted  and  separated  therefrom,  such 
oils  and  denser  substances  being  purified  in  the  manner  above 
described  in  reference  to  the  heavier  and  lighter  naphthaline  oils 
and  the  naphthaline  Sealed  Nov.  5,  1852.    Chem.  Gazette^ 
SACCHARINE  CARBONATE  OF  IRON  AND  MANGANESE. 
By  T.  S.  Speer,  M.  D.,  of  Cheltenham. 
The  introduction  of  the  metal  manganese  into  the  domain  of 
therapeutics,  due,  I  believe,  in  the  first  instance,  to  the  Belgian 
physician  M.  Hannon,  has  within  the  last  two  years  been  followed 
by  a  careful  investigation  of  its  medicinal  properties  on  the  part 
of  several  French  physicians. 
From  them,  it  would  appear  that  this  metal  when  given  in  com- 
bination with  iron,  is  capableof  rendering  signal  services  in  those 
diseases  where  iron  alone  has  been  hitherto  prescribed,  and  at  the 
present  moment,  the  ferro-manganic  preparations  hold  a  prominent 
place  in  continental  practice.  As  I  am  not,  however,  aware  that 
they  have  yet  undergone  a  trial  in  this  country,  or  at  least  one, 
the  results  of  which  have  been  made  public,  I  venture  to  state 
shortly,  what  a  limited  experience  of  two  years  enables  me  to  say 
upon  this  subject  ;  inasmuch  as  during  that  period  I  have  embraced 
every  legitimate  opportunity  of  prescribing  the  combination 
mentioned  at  the  head  of  the  present  communication. 
In  a  paper  published  in  the  Revue  Medico- Chirurgicale  for 
June,  1849,  M.  Hannon  first  suggested  the  following  preparations 
or  manganese,  viz.,  the  carbonate,  the  tartrate,  the  phosphate,  the 
neutral  malate,  and  the  iodide.  With  none  of  these  was  a  similar 
salt  of  iron  associated. 
M.  Petrequin,  of  Lyons,  however,  having  taken  up  the  subject 
of  manganic  preparations,  published  in  the  Bulletin  General  de 
Therapeutique  for  March  the  15th  and  30th,  1852,  two  papers 
containing  the  results  of  his  experience  relative  to  the  utility  of 
the  metal  in  question  when  administered  in  conjunction  with  iron. 
The  preparations  employed  by  him  consisted  chiefly  of  the  iodide 
and  lactate  of  iron  and  manganese  in  the  form  of  syrup,  and  of  the 
carbonate  of  the  two  metals  in  the  form  of  pill. 
Being  desirous  of  trving  the  effects  of  such  a  combination  in 
