ON  LEPTANDKIIN, 
505 
the  results  of  substituting  sulphate  of  cinchona  for  sulphate  of 
quinia  in  intermittent  fever,  and  so  successful  did  it  prove  that 
he  has  since  continued  to  use  it  in  his  hospital  practice.  In 
April  last,  at  the  suggestion  of  Dr.  Conrad,  Dr.  Pepper  made  a 
trial  of  sulphate  of  quinidin  (the  third  alkaloid  in  cinchona  bark,) 
in  several  cases  of  intermittent,  with  such  decided  success,  that 
he  is  disposed  to  believe  that  quinidin  is  more  active  than  either 
of  the  other  alkaloids.  These  results  corroborate  a  similar  trial 
in  two  obstinate  cases  of  intermittent,  by  Dr.  Helfrick  of  this 
city,  which  had  a  like  result.  If  these  observations  are  supported 
by  other  testimony,  we  shall  not  hear  of  the  rejection  of  cinchona 
barks  because  in  the  aggregate  of  alkaloids  there  happens  to  be 
less  than  one  per  cent,  of  quinia. — Ed. 
Medical  Statistics. — According  to  the  statistical  tables  of 
the  census  of  1850,  there  are  in  the  United  States  and  Territo- 
ries, 40,564  Physicians,  191  Surgeons,  6,139  Apothecaries  and 
Druggists,  465  Chemists,  2,923  Dentists,  10  Oculists,  59  Patent 
Medicine  Makers,  and  943  Professors.  Of  these,  1,060  Physi- 
cians, 54  Apothecaries,  8  Oculists,  563  Dentists,  and  26  Nostrum 
Makers,  are  found  in  the  State  of  New  York  alone,  viz.,  one 
eighth  of  the  physicians  and  one-sixth  of  the  apothecaries. — 
New  York  Med.  Gazette. 
Antimoniate  of  Quinia  Dr.  La  Camera,  of  Naples,  has 
suggested  the  use  of  antimoniate  of  quinia,  in  intermittents,  of 
great  efficacy.  The  Bulletin  de  Therapeutique  corroborates  its 
merits  and  suggests  further  trials.  This  salt  is  supposed  to  em- 
brace in  its  effects  the  resolvent  and  diaphoretic  properties  of 
the  antimonials  and  the  virtues  of  cinchona.  «  The  dose  of  an- 
timoniate of  quinia  is  12  or  15  grains,  in  broken  doses,  during 
the  interval  of  remission." — Virginia  Med.  and  Surg.  Jour. 
LEPTANDRIN — THE  RESINOUS  PRINCIPLE  OF  THE  ROOT  OF 
•  LEPTANDRA  VIRGINICA. 
(From  the  American  Eclectic  Dispensatory , page  595.) 
Leptandrin  may  be  prepared  as  follows  : — Take  of  coarsely 
powdered  Leptandra  any  quantity,  alcohol  90  per  cent.,  a  suffi- 
cient quantity.  By  percolation  obtain  a  saturated  tincture. 
Place  the  tincture  in  a  still  and  distil  off  the  alcohol,  and  while 
