824 
MANUFACTURE  OF  THE  OTTO  OF  ROSE. 
impregnated  with  the  color  and  taste  of  the  root.  When  we 
consider  the  comparative  insolubility  of  the  isolated  resinous  and 
coloring  principles  of  rhubarb,  it  is  surprising  how  large  a 
quantity  may  be  extracted  by  the  slow  action  of  cold  water  in 
this  way.  I  believe  that  for  treatment  with  cold  water,  rhubarb 
should  be  in  powder  of  at  least  40  meshes,  if  not  30,  so  that  it 
will  be  more  porous. 
5.  Two  ounces  of  powdered  columbo  was  treated  in  the  same 
mann  r ;  the  absorption  was  nearly  as  slow  as  in  the  rhubarb, 
about  10  hours  elapsing  before  it  commenced  to  pass  out  below, 
and  14  hours  longer  were  required  to  fill  an  eight  ounce  vial. 
On  examining  the  product  it  was  found  that  the  first  three 
ounces  were  dense  and  dark  colored,  the  liquid  above  being 
gradually  less  colored,  but  quite  bitter.  The  mass  did  not  swell 
as  much  as  the  gentian.  The  result  would  indicate  the  impro- 
priety of  so  fine  a  powder  for  columbo,  because  of  the  slow  pas- 
sage of  the  menstruum,  and  its  tendency  to  decompose  in  warm 
weather  before  the  root  is  exhausted — even  with  the  use  of  the 
funnel. 
All  of  these  substances  with  diluted  alcohol,  would  have  be- 
haved much  better  and  the  results  obtained  more  quickly,  yet 
the  experiments  serve  to  illustrate  the  influence  of  a  conical 
percolator. 
ON  THE  MANUFACTURE  OF  THE  OTTO  OF  HOSE  AT  KISANLIK 
IN  EUROPEAN  TURKEY. 
By  J.  Lawrence  Smith,  M.  D. 
Professor  of  Chemistry  in  the  University  of  Louisville. 
Seeing  an  article  in  the  May  number  of  the  Journal  of  Phar- 
macy on  the  Otto  of  Rose,  brought  to  my  recollections  some 
neglected  notes  made  during  my  residence  in  Turkey,*  on  the  cul- 
ture of  the  rose  and  the  extraction  of  its  oil  at  Kisanlik  in  the 
Balkan  Mountains. 
Having  succeeded  in  finding  those  notes,  and  as  they  contain 
matter  which  may  interest  some  of  your  readers,  I  forward  them 
for  publication. 
*  [Note. — Prof.  Smith  was  engaged  during  two  years  in  the  geological 
survey  of  Turkey,  under  the  patronage  of  the  Sultan. — Editor.] 
