Am.  Jour.  Pharm. ) 
Feb.,  1881.  I 
Waldivin  and  Cedi^in. 
73 
were  obligingly  furnished  him  by  Mr.  E-estrepo.  Only  that  of  the 
waldivia  was  obtained  crystalline^  and  this  is  now  called  waldivin. 
Preparation. — The  finely-powdered  waldivia  is  extracted  with  alco- 
hol of  70  per  cent.,  and  then  distilled.  The  residue  while  still  warm 
is  agitated  with  a  large  quantity  of  chloroform^  which  takes  up  the 
waldivin,  and  the  carefully  separated  chloroformic  liquid  is  then  dis- 
tilled to  dryness,  the  latter  residue,  when  taken  up  again  with  boiling 
water,  separates,  on  cooling,  the  waldivin  in  crystals.  The  yield  is  very 
variable,  according  to  the  fruits ;  thus  from  1  part  to  1000,  of  badly 
preserved  fruits,  it  may  amount  to  as  much  as  8  from  recent  and  dry 
waldivias. 
Composition. — The  crystals  of  waldivin  contain  water  of  crystal- 
lization, and  their  composition  may  be  represented  by  the  formula 
C36H24O20.5H2O.  When  heated  to  110°C.  they  lose  10  per  cent.,  and 
the  formula  requires  9'8  per  cent.;  on  the  other  hand,  the  analysis  of 
the  anhydrous  body  has  given  the  following  results : 
Found.  Calculated  for  C3fiH24O.20 
I.  IL 
C    54-40         54-2  54' 
H    6-22  6-3  6- 
O    39-38         39-5  40- 
100-00         100-0  100- 
Physical  Properties. — The  waldivin  crystallizes  in  hexagonal  j^risms, 
terminated  by  a  double  hexagonal  pyramid  ;  it  has  the  specific  gravity 
1*46,  and  when  heated  loses  its  water  of  crystallization,  then  melted  at 
about  230 °C.  it  becomes  colored,  but  is  not  volatile,  and  possesses  no 
rotatory  power.  It  is  very  sparingly  soluble  in  cold  Avater  (600  parts 
at  15°C.),  but  dissolves  in  30  parts  of  boiling  water,  acids  and  salts 
increasing  its  solubility  considerably,  and  its  aqueous  solutions  froth 
strongly  upon  agitation  ;  it  dissolves  in  60  parts  of  70  per  cent,  alcohol 
at  15°C.,  but  requires  190  parts  of  absolute  alcohol.  Chloroform  dis- 
solves it  abundantly,  ])ut  it  is  insoluble  in  ether.  It  possesses  an 
extreme  bitterness. 
Chemical  Properties. — The  waldivin  is  neutral,  its  aqueous  solutions 
are  precipitated  by  tannin,  and  by  ammoniacal  acetate  of  lead ;  the 
neutral  and  basic  acetates  of  lead  do  not  precipitate  it.  In  the  cold, 
sulphuric  and  nitric  acids  dissolve  it  without  appearing  to  produce 
any  sensible  alteration,  the  solutions  not  being  precipitated  on  the 
addition  of  water ;  but  if  the  solutions  be  neutralized  by  means  of  an 
