166  Researches  on  the  Cinehona  Alkaloids.      { ^'"Aprium!""*" 
into  the  hydrochlor  compounds.  To  this  purpose  the  hydrochlorapo- 
bases  were  treated  for  some  hours  with  acetic  anliydride  between  60° 
and  80°C.;  after  the  addition  of  water,  the  sohition  was  evaporated  at 
the  same  temperature,  the  residue  taken  up  with  cold  water  and  pre- 
cij^itated  by  ammonia.  The  precipitate  was  then  shaken  with  ether,, 
this  sohition  washed  with  water,  and  in  some  cases  also  treated  with 
animal  charcoal,  then  allowed  to  slowly  evaporate.  By  this  treatment 
the  acetic  ethers  of  the  hydrochlorapo-bases  were  obtained,  and  in 
accordance  witli  former  observations,  with  hydrochlorapoquinia  and 
hydrochlorapoquinidia  the  diacetyl  ethers,  with  the  others  the  mon- 
acetyl  ethers.  All  of  these  compounds  are  easily  saponifietl  by  boiling 
witli  alcoholic  potassa  solution,  when  the  hydrochlorapo-bases  are  again 
regenerated. 
DlaGetyl-hydroGhlorcipoqidrda,  C^(^^^{Q^fi\CV^jJ2^  is  obtained 
from  ether  in  beautiful  colorless  prisms,  which  melt  at  184°C.  (uncorr.) 
It  dissolves  readily  in  dilute  sulphuric  acid,  produces,  however,  neither 
with  this  nor  with  acetic  acid  a  blue  fluorescence.  Ammonia  and 
caustic  soda  give  white,  flocculent  precipitates,  which  dissolve  quite 
readily  in  the  latter  precipitant.  The  alkaloid  is  Isevogyrate,  dissolves 
readily  in  alcohol  and  chloroform,  but  with  difficulty  in  ether.  Its 
chloroplatinate  is  a  beautiful  yellow,  flocculent  precipitate,  at  first 
amorphous,  but  soon  becoming  crystalline. 
Diacetyl-hydrochlorapoquinidia,  C29H2i(C2H30)2ClN202,  is  in  small^,. 
colorless,  rhombic  scales,  melting  at  168°C.  (uncorr.),  sj^aringly  soluble 
in  etlier,  but  readily  in  alcohol  and  chloroform.  It  has  a  bitter  taste,,, 
and  shows  in  alcoholic  solution  a  decided  alkaline  reaction  ;  its  solution 
in  dilute  sulphuric  acid  shows  no  fluorescence,  and  its  alcoholic  solution 
is  not  colored  by  chlorine  and  ammonia.  Its  rotation  for  the  solution 
in  water  with  3HC1  is  -f  94'6°.  This  solution  gives  with  an  excess 
of  ammonia  or  caustic  soda  white  flocculent  precipitates,  which  are 
soluble  to  some  extent  in  the  precipitant.  The  platinum  salt  is  a 
yellow,  flocculent  precipitate. 
Acetyl-hydrochlorapocinehonidia,  CVjTl22(C2H30jClN20,  is  in  white' 
shining  prisms,  melting  at  150°C.  (uncorr.),  dissolves  quite  readily  in^ 
ether,  alcohol  and  chloroform,  and  very  readily  in  dilute  acids;  ammo- 
nia produces  in  the  latter  solutions  a  white  flocculent  precipitate,  which 
dissolves  to  a  considerable  extent  in  the  precipitant.  The  alkaloid^ 
like  the  original  substance,  deviates  the  plane  of  polarized  light  to  the: 
