PractiGol  Notes  from  Foreign  Journals,  '249 
Piiiil  Merres  in  different  proportions,  and  kept  in  tlie  state  of  powder 
$us  well  as  in  pills,  in  a  room,  in  the  cellar  and  in  the  drying  closet,  in 
the  latter  at  a  teniperatnre  of  38  to  45°C.  After  9  months  the  pow- 
ders and  pills  were  examined  for  corrosive  snblimate,  by  treatment 
with  alcohol  and  testing  the  solution  with  and  with  metallic 
<*opper;  not^a  trace  of  mercuric  chloride  was  detected.  It  was  proven 
by  control  experiments  that  by  the  means  indicated  mercury  could  be 
detected  in  the  solutions  in  a  dilution  of  1  in  20,000. — Archiv  d. 
Phar.,  Feb.,  1881,  p.  1.3o. 
Chinoidin  borate  is  pre])ared  by  De  Vrij  by  heating  2  parts  of  chin- 
<oidin  and  1  part  of  boric  acid  with  20  parts  of  distilled  water  just  to 
boiling,  and  filtering  the  liquid,  after  a  few  moments  rest,  through  a 
plug  of  moist  cotton,  in  order  to  separate  some  resinous  particles.  The 
undissolved  portion  yields^  after  drying  and  triturating,  a  brown  pow- 
der, infusible  upon  the  water-bath,  and,  though  soluble  in  dilute  min- 
•eral  acids,  consisting  of  several  unknown  compounds,  but  free  from 
that  alkaloid  to  which  the  name  chinoidin  properly  belongs,  namely, 
Hesse's  diconchinia.  This  has  been  dissolved  by  the  aid  of  the  boric 
acid.  The  clear  solution  is  heated  to  boiling,  when  a  turbidity  and  the 
^separation  of  a  dark  brown  resinous  body  takes  place,  from  which  the 
<;lear  liquid  is  decanted.  The  heating,  just  to  boiling,  is  repeated  until 
no  further  separation  occurs,  and  the  resulting  turbidity  completely 
disappears  on  cooling.  The  liquid  is  evaporated  to  the  weight  of  the 
'chinoidin  used,  set  aside  over  night  at  a  temperature  not  exceeding 
15°C.,  and  then  separated  from  the  excess  of  boric  acid,  which  has 
^crystallized  out  and  may  be  reserved  for  a  subsequent  operation.  The 
clear  liquid  is  then  evaporated  by  meas  of  a  water-bath  to  a  dry  yel- 
lowish powder,  or  it  is  dried  in  scales. 
Well  prepared  chinoidin  borate  ^delds  with  3  parts  of  cold  water  a 
clear  dark  yellow  solution,  having  an  alkaline  reaction  to  test  paper. 
The  10  per  cent,  solution  remains  perfectly  clear  on  the  addition  of  a 
few  drops  of  solution  of  sodium  hyposulphite.  A  solution  of  1  gram 
of  the  borate,  agitated  with  a  little  caustic  soda  and  chloroform,  yields 
a  chloroform  solution  which  on  evaporation  leaves  at  least  0*54  gram 
iimorphous  alkaloid.  Chinoidin  borate  is  somewhat  hygroscopic,  and 
nmst  be  kept  in  well  closed  bottles. — Phar.  Zeitg.,  1881,  p.  162,  from 
Nieiiic  Tijdschr.,  Feb. 
Quinia  Sulphate  and  Ilusc. — Bagros  observed  wjiilc  making  pills 
that  the  odor  of  muse  completely  disappeared  and  that  of  liquorice 
.'   Am.  Jour.  PlTaini. ) 
May,  1881.  j 
