Am.  Jour.  Pharm. ) 
June,  1881.  } 
Sanguinaria  Canadensis. 
211 
inclined  toward  a  grey-brown  color.  The  resin  {y)  that  is  solul^le  in 
cold  alcohol,  is  of  a  ])right  red  color,  extract-like  consistence,  has 
a  slight  taste,  and  colors  the  saliva     Their  behavior  to  solvents,  etc.. 
Carbon 
Wafer.        DisulpMde.  Benzol. 
Sufficient  to  Spar,  solu-  Spar.  sol. 
color  only,  l)le,  hot  or  h  o  t ;  less 
hot  or  cold.-      cold.  sol.  cold. 
Scarcely  co-  Soluble  hot,  Soluble  hot, 
lors,  hot  spar,  solu-  spar,  solu- 
or  cold.  ble  cold.         ble  cold. 
Hydrochloric 
Ammonia.         Acid.  Incinernikjn. 
Very   spar.    Soluble  hot, 
sol.  hot  or      spar,  solu-   No  ash. 
cold.  ble  cold. 
Spar.    sol.    Soluble  hot, 
hot,  iusol.      spar,  solu-  Ash. 
cold.  Me  cold. 
The  resin  (ct)  was  examined  for  protocatechnic  acid  as  follows : 
Eqnal  parts  of  the  resin  and  solid  canstic  potassa  were  heated  together 
in  a  silver  dish  until  completely  fused.  The  dark  colored  fused  mass 
thus  obtained  was  dissolved  in  water,  the  aqueous  solution  rendered 
slightly  acid  by  sulphuric  acid,  and  filtered ;  the  yellowish-colored 
filtrate  was  then  agitated  with  ether  until  it  ceased  to  take  up  any  more 
soluble  matter ;  the  ether  was  then  separated  and  evaporated  sponta- 
neously, furnishing  a  small  amount  of  crystals,  which  gave  with  ferric 
chloride  a  bright  emerald-green  color,  and  on  the  subsequent  addition 
'of  a  weak  solution  of  potassium  hydrate  a  bright  crimson-red  color 
was  produced,  making  it  quite  conclusive  that  protocatechnic  acid  was 
formed  by  the  above  treatment. 
Resin  (x)  gave  the  same  indications  for  protocatechnic  acid  Avhen 
rsimilarly  treated. 
Examination  of  Resinous  Precijntates  in  Tincture^  etc. — The  precipi- 
tates formed  in  the  liquid  preparations  of  Sanguinaria  on  standing  were 
also  examined  to  ascertain  whether  sanguinarina  was  carried  down  with 
the  resinous  matter.  Messrs.  Bullock  &  Crenshaw,  and  Wm.  E. 
Warner  &  Co.,  very  kindly  furnished  me  with  sufficient  quantities  of 
the  precipitate  from  the  tincture  and  fluid  extract,  which  were  exam- 
ined as  follows :  The  drained  precipitate  was  thoroughly  washed  with 
a  mixture  of  alcohol  3  parts,  water  1  part,  and  then  l)oiled  ^vitli  acid- 
ulated water  (water  15  parts,  acetic  acid  1  part),  filtered,  thus  se])arat- 
was  found  to  be  as  follows : 
Resin 
{X) 
Resin 
[y) 
Resin 
{X) 
Resin 
Ether. 
Spar,  solu- 
ble, hot  or 
cold. 
Very  spar, 
sol.  hot  or 
cold. 
Oasolin. 
Spar,  solu- 
ble, hot  or 
cold. 
1 11  s  o  1  u  ble, 
hot  or 
cold. 
Chloroform . 
Spar,  solu- 
ble, hot  or 
cold. 
Soluble,  hot 
or  cold. 
Caustic 
Potassa  Sol. 
Spar.  sol. 
hot;  less 
sol.  cold. 
Sufficient  to 
color,  hot 
or  cold. 
