"^'"jliT^'isSi""}    Otucose  as  an  Ex  dp  lent  for  Fill  Ifasses.  327 
aloes  socotr.  aa  gr.  x  were  made,  using  6  grains  of  glucose  and  6  grains 
of  the  glycerites,  respectively.    The  latter  became  quite  hard  in  a  short 
time.    Immersed  in  water,  those  niade  with  glucose  and  glycerite  of 
starch  were  disintegrated  in  about  the  same  length  of  time,  while 
hour  additional  time  was  required  for  those  containing  tragacanth. 
Resins  and  Gum  Resins. — The  trituration  of  these  substances  with 
alcohol,  as  recommended  by  Hager  and  others,  does  not  give  the  best 
results,  too  much  time  and  patience  being  required  for  obtaining  the 
proper  consistency.  In  most  cases  the  mass  is  readily  formed  with 
glucose,  which  seems  to  have  the  elfect  of  softening  the  substance. 
Guaiacum  resin,  however,  is  an  exception,  since  too  much  time  is 
necessary  for  forming  a  pill  mass  with  glucose;  but  the  addition  of  a 
minute  quantity  of  tragacanth  aided  the  operation  in  a  marked  degree. 
For  Resina  guaiaci  gr.  xxiv,  16  grains  of  glucose  and  15  grains  of 
glycerite  of  starch  were  used,  the  latter  requiring  the  addition  of  a 
little  powdered  liquorice  root.  Both  kinds  of  pills,  after  remaining  in 
water  for  12  hours,  had  separated  into  particles  floating  in  the  water. 
Mastiche  gr.  xxiv  yields,  with  16  grains  of  glucose,  a  very  satis- 
factory result,  the  pills  being  of  a  clear,  pale  yellow  color  when  finished. 
When  glycerite  of  starch  Avas  used,  a  little  tragacanth  had  to  be  added  ; 
but  glycerite  of  tragacanth  did  not  give  a  satisfactory  result  (also  not 
with  resin  of  guaiacum).  The  mastic  pills  with  glucose  were  completely 
disintegrated  in  5  minutes,  those  with  glyceril:eof  starch  in  15  minutes. 
In  Pilulse  aloes  et  asafoetidse,  U.  S.  P.,  the  soap  (32  grs.)  can  be 
advantageously  replaced  by  glucose  (24  grs.)  when  rapid  solubility  is 
a  point  of  consideration,  the  latter  dissolving  in  one-half  the  time 
necessary  for  those  made  with  soap. 
Glucose  may  also  with  advantage  be  substituted  for  the  syrup  in 
the  formula  for  Pil.  galbani  comp.,  U.  S.  P. 
Cinchona  Alkaloids. — Of  the  numerous  excipients  heretofore  recom- 
mended glycerin  is  probably  the  best  for  the  production  of  an  elegant 
white  quinia  or  cinchonidia  pill,  but  a  comparative  trial  will  prove, 
both  as  regards  manipulation  and  appearance,  that  glucose  is  superior. 
For  Quinise  sulphas  gr.  vi,  3  grains  of  glucose,  and  for  Cinchonidise 
sulphas  gr.  xii,  5  grains  of  glucose  were  used.  The  pills  are  made 
readily  in  less  time,  and  are  of  smaller  size  than  when  made  with  most 
other  excipients. 
Quinia  sulphate  and  exsiccated  ferrous  sulphate,  of  each  6  parts, 
were  made  into  pills,  using  in  the  one  case  5  parts  of  glucose,  and  in 
