AmAprnr,'i897frm*}    Marrubiin  and  its  Dichlorme  Derivative.  207 
trated.  From  concentrated  hot  alcoholic  solutions,  it  crystallizes 
in  dull-white  plates. 
It  is  soluble  in  acetone,  ether,  alcohol,  chloroform,  but  most  readily 
in  hot  benzol. 
It  is  insoluble  in  petroleum  benzin  and  cold  water,  and  only  spar- 
ingly soluble  in  hot  water.  . 
Marrubiin,  when  tested  for  nitrogen,  by  fusing  a  small  quantity  of 
it  with  a  fragment  of  metallic  sodium,  agitating  the  heated  mass 
with  water  filtering,  and  adding  ferrous  sulphate,  ferric  chloride  and 
hydrochloric  acid  in  excess,  did  not  give  the  characteristic  blue 
precipitate  or  color  of  ferric  ferrocyanide,  (Fe2)2  (Fe  (CN)6)3,  thus 
indicating  the  absence  of  nitrogen. 
The  crystals  obtained  by  recrystallization  from  hot  alcohol,  pre- 
vious to  being  treated  with  animal  charcoal,  melted  at  I58°-I59°  C. 
They  were  subjected  to  ultimate  analysis ;  the  combustions  were 
made  in  an  open  tube  with  copper  oxide  and  a  current  of  oxygen, 
the  substance  being,  in  all  cases  of  combustion,  previously  dried  in 
a  desiccator  over  sulphuric  acid  for  twenty-four  hours. 
The  following  are  the  results  of  two  combustions : 
(1)  '1931  gramme  of  the  substance  yielded: 
•5113  gramme  of  C02  =  72*19  per  cent,  of  C. 
•1500       "       "H20  =     8-59  "      "  "H. 
19-22  "      "     "  O. 
(2)  -1659  gramme  of  the  substance  yielded  : 
•4414  gramme  of  C02  =  72*57  per  cent,  of  C. 
•1293       "       "  H20  =     8-68  "     "     "  H. 
1875  "     "     "  o. 
IOO'OO 
The  crystals  were  then  recrystallized  six  times  from  hot  alcohol, 
and  a  second  determination  of  the  melting  point  gave  the  same 
result  as  that  obtained  in  the  previous  case,  viz.:  i58°-i59°  C. 
They  were,  therefore,  treated  with  animal  charcoal  in  several  suc- 
cessive applications,  and  the  melting  point,  as  proven  by  several 
trials,  was  found  to  be  I54°-I55°  C.  A  combustion  of  the  purified 
substance  showed  the  following  to  be  its  percentage  composition, 
