602 
Progress  in  Pharmacy. 
{ 
Am.  Jour.  Pharm . 
December,  1902. 
After  dissolving  the  oils  in  the  alcohol,  mixed  in  a  suitable  bottle,  the  mix- 
ture is  allowed  to  stand  for  twenty-four  hours,  occasionally  shaking.  Then  add 
Shake  occasionally,  and  allow  to  stand  for  another  twenty-four  hours.  Filter. 
A  perfectly  clear  and  sparkling  product  is  much  more  readily- 
obtained  than  with  the  U.S. P.  process. 
Bismutose. — Reinhardt  {Pharm.  Zeitung,  1902,  p.  637)  gives  an 
outline  of  the  method  of  preparation  and  the  physical  properties 
of  a  trade-marked  and  patented  substitute  for  subnitrate  of  bis- 
muth. Bismutose,  from  this  description,  appears  to  be  an  unstable 
mixture  of  bismuthyl  and  albumin,  and  is  supposed  to  have  the 
advantage  of  being  absolutely  innocuous  even  in  continued  large 
doses. 
Croton  Oil,  detection  of,  in  tincture  of  iodine.  Durien  [Pharm. 
Centralhalle,  1902,  p.  447,  from  Bulletin  des  Sciences  Pharmacology) 
directs  that  70  grammes  of  water  be  added  to  10  grammes  of  the 
suspected  tincture  of  iodine.  An  excess  of  iron  filings  is  then  added 
to  combine  with  the  iodine  present,  forming  iodide  of  iron.  The 
solution  is  then  thoroughly  well  shaken  with  a  small  quantity  of 
ether,  and  this  is  later  allowed  to  evaporate.  The  presence  of  a 
fatty  oil  is  indicated  by  a  residue,  which  residue  may  be  tested  for 
its  identity  by  its  action  on  the  skin,  odor,  and  brown  coloration 
with  sulphuric  acid. 
Diosmal. — Under  this  title  Paul  Runge  [Pharm.  Centralhalle,  1902, 
p.  465)  describes  the  physical  properties  and  an  outline  of  the 
preparation  of  a  petroleum  ether-alcoholic  extract  of  buchu  leaves. 
This  preparation  is  made  by  successively  extracting  buchu  leaves 
with  petroleum  ether  and  strong  alcohol,  distilling  off  the  solvents 
and  ultimately  mixing  the  residual  extractives.  Dose,  o-io  or  more 
three  times  a  day. 
Hellebore. — A.  Tschirch  communicates  [Schweiz.  Wochenschr., 
1902,  p.  410)  a  comparative  study  of  a  number  of  varieties  of 
hellebore  rhizomes  made  with  the  assistance  of  E.  Neuber.  This 
paper  includes  a  study  of  the  rhizomes  and  roots  of  Helleborus  viridis, 
Helleborus  niger,  Helleborus  foetidus,  Helleborus  caucasicus  and  Helle- 
borous  purpurascens.  The  writers  also  call  attention  to  and  describe 
a  number  of  drugs  that  are  sometimes  mistaken  for  or  substituted 
for  hellebore. 
Water  
Calcined  magnesia 
1,500*  c.c. 
25*  gm. 
