Am.  Jour.  Pharm.  \ 
December,  1902.  J 
Progress  in  Pharmacy. 
603 
Isarol,  formerly  called  ichthyodin,  a  Swiss,  and  Petrosulfol,  an 
Austrian  substitute  for  ichthyol,  are  both  said  to  be  obtained  from 
the  same  base,  and  to  correspond  to  all  the  requirements  of  the 
Swiss  Pharmacopoeia  for  ammonium  sulfoichthyolicum. 
Lecithol  is  the  trade-name  for  a  preparation  of  lecithin  made  by 
the  chemische  fabrik  J.  D.  Riedel,  Berlin.  Lecithin,  the  name 
applied  to  the  widely  distributed  combination  of  glycerinophos- 
phoric  and  fatty  acids  with  cholin,  has  attracted  quite  considerable 
attention  during  the  past  year,  and  it  is  quite  probable  that  the 
near  future  will  see  a  number  of  preparations  on  the  market,  of 
which  this  appears  to  be  one  of  the  first. 
Local  anesthetics:  Substances  that  have  local  anesthetic  proper- 
ties are  always  of  interest.  Among  the  chemical  substances  that 
have  been  experimented  with  in  this  direction  are: 
Dionin. — Darien  (Jour,  des  Practiciens,  1902,  p.  131)  has  em- 
ployed a  I  per  cent,  solution  of  dionin  in  the  eye  for  the  relief  of 
pain.  Darien  also  recommends  dionin  for  the  relief  of  pain  caused 
by  a  decayed  tooth. 
Acoin. — Darien  in  the  same  article  also  says  that  this  substance 
produces  local  anesthesia  only  when  the  epithelium  is  destroyed. 
Its  action  is  said  to  be  slower  and  more  prolonged  than  cocaine.  It 
has  been  employed  as  a  local  anesthetic  in  connection  with  subcu- 
taneous injections  of  irritating  substances,  such  as  corrosive  subli- 
mate or  iodine.  Satisfactory  results  have  also  been  obtained  by 
mixtures  of  cocaine  and  acoin. 
Mesotan,  a  derivative  of  salicylic  acid  (the  alkyloxymethylester 
of  salicylic  acid),  is  offered  as  a  substitute  for  methyl  salicylate  and 
true  oil  of  wintergreen  for  external  use.  It  is  said  to  be  free  from 
the  objectionable  and  persistent  odor  of  oil  of  wintergreen,  and 
preferable  on  this  account.  Mesotan  is  soluble  in  ether,  alcohol,  or 
fatty  oils,  and  is  said  to  be  readily  absorbed  through  the  unbroken 
skin  (Pharm.  Centialhalle.,  1902,  p.  506)." 
Pancreatized  Cod-Liver  Oil. — The  Chemist  and  Druggist  (accord- 
ing to  the  Pharm.  Zeit.,  1902,  p.  639)  brings  the  following  formula: 
Cod-liver  oil  150  c.c. 
Water     .  50  c.c. 
Extract  of  malt  200  c.c. 
Pancreatin  (soluble)   1  gm. 
Sodium  chloride   2  gm. 
Sodium  bicarbonate   2  gm. 
