RESEARCHES ON CINCHONINE. 
257 
all correspond to the 
formula C 
20 H 12 NO, 
and are 
as follows 
I. 
II. 
III. 
IV. 
V. 
Carbon. . . . 77'78 
77-75 
78-24 
78-15 
78-06 
Hydrogen . . 7*72 
7-80 
7-73 
7-75 
7-67 
VI. 
VII. 
VIII. 
IX. 
X. 
Carbon 78*15 
78-15 
78-24 
78-08 
77-57 
Hydrogen . . 7'62 
7' 64 
7-73 
7-28 
7.65 
When a solution of cinchonine 
in alcohol acidulated with muri 
atic acid is precipitated with bichloride of platinum, a crystalline 
precipitate of a light yellow, at first almost white color is obtained. 
This yields on analysis numbers which only accord with Laurent's 
formula C 38 H 22 N 2 O 2 , so as to lead to the supposition that in the 
treatment with bichloride of platinum, C 2 H 2 had been eliminated 
in one form or the other. Experiments in this direction however 
showed nothing of the sort ; on the contrary, it was found that in 
order to obtain a platinum salt corresponding to the formula C 20 
H 12 N 0, the precipitate of the cinchonine with bichloride of pla- 
tinum must be redissolved in water, which requires very long ebul- 
lition. On cooling, a whitish pulverulent precipitate first makes 
its appearance, and after long standing, a dark yellow, very beau- 
tifully crystallized platinum salt separates, which had the follow- 
ing composition : — 
Carbon 33-1 20 33'3 
Hydrogen 3"6 . . 12 3*3 
Nitrogen . . 1 
Oxygen . . 1 
Platinum 27'38 27-34 1 27-36 
Chlorine . . 2 
The alkaloid separated from this platinum salt by sulphurretted 
hydrogen gave, after recrystallization, on analysis, numbers agree- 
ing with the preceding : — 
Carbon 77-83 20 77*92 
Hydrogen . . . 7*65 12 7-79 
The cinchonines of commerce are very variable preparations. 
Besides the one which contained jS-quinine, the author analysed a 
beautifully white crystallized cinchonine, which was mixed with a 
mere trace of amorphous powder. It furnished : — 
23 
