306 
IODIDE OF QUINIUM, ETC. 
decomposed by spontaneous evaporation, as iodide of potassium in 
cubical crystals separates to some extent. 
I have formed in a manner analagous to that used in making the 
preceding compounds, salts in which bromine replaced the iodine, 
with quinia and cinchonia. They are all white or brownish-white 
preparations, more soluble in water than the iodides, and forming 
larger crystals. I have succeeded in making several compounds 
in which iodide of sodium replaced iodide of potassium. 
The term podophylline is applied to the resin of podophyllum 
pellatum by the so-called " eclectic practitioners." As prepared 
by them, the alcoholic tincture of the root is distilled to remove 
the alcohol, and the resin which separates as the alcohol distils off 
is removed from the watery liquid, dried and powdered. I consider 
a better mode is to concentrate the tincture till most of the alcohol 
is evaporated, and throw the residue into water when the resin 
precipitates. The consistence of the resinous liquid before pre- 
cipitation by water is important, because if too concentrated the 
resin separates in clots, and is not easily washed. In its purest 
state this resin is colorless. See the Inaugural Essay of Mr. John 
R. Lewis, Amer. Jour. Pharm., Vol. xix. page 165. 
This resin of podophyllum will purge a susceptible person quite 
thoroughly five or six times, the last evacuations being very 
watery and copious. Two grains will purge actively persons of 
ordinary susceptibility, and three grains will generally suffice for 
almost any one. Some persons experience nausea and even vomit, 
though 1 do not know that they are more affected by this article 
than by any other active cathartic. The eclectics also prepare 
Macroytin from the root of Cimicifuga racemosa, Leptandrin from 
Leptandra virginica, and Sanguinarin from Sanguinaria cana- 
densis. The latter substance is to be distinguished from the San- 
guinaiina of Dana, which is an alkaloid. I have prepared some 
t of the sulphate of sanguinarina by the process given in Silliman's 
Journal, 1831, Vol. 2d, page 503 and 504. Dr. William Taylor, 
of this neighborhood, has used this sulphate as an expectorant in 
lung diseases, and has been very favorably impressed by its action. 
He used it in cbses of about one-fourth of a grain. 
I have also prepared the "preserved juice" of Conium macula- 
turn, (see U. S. Disp., 6th edit., p. 1159,) by adding one part of 
alcohol to two parts of the recent juice and filtering. It appears 
