CHEMICAL  COMPOSITION  OF  QUINIDINE. 
165 
few  which  are  not  distinctly  crystallizable ;  some  furnish  beau- 
tiful large  crystals  with  a  vitreous  brilliancy.  The  aqueous 
solutions  of  the  quinidine  salts  yield  with  potash,  soda  and  ammonia, 
the  mono-  and  the  bicarbonates  of  the  alkalies,  white  pulverulent 
precipitates,  which  crystallize  after  long  standing,  and  are  insolu- 
ble in  an  excess  of  the  precipitant. 
Phosphate  of  soda,  bichloride  of  mercury,  and  nitrate  of  silver, 
yield  white  precipitates.  Chloride  of  gold  gives  a  light  yellow, 
chloride  of  platinum  an  orange-yellow,  and  chloride  of  palla- 
dium a  brown  precipitate.  Sulphocyanide  of  ammonium  yields 
a  white  and  tannic  acid,  a  dirty  yellow  color,  with  the  salts 
of  quinidine. 
Neutral  Sulphate  of  Quinidine. — This  salt  was  prepared  by 
dissolving  quinidine  in  diluted  sulphuric  acid,  till  the  latter  was 
neutralized.  The  neutral  solution  having  been  evaporated  in  the 
water-bath,  yielded  by  cooling  long  silky  shining  acicular  crystals, 
arranged  in  star-like  groups,  of  sulphate  of  quinidine,  the  watery 
solution  of  which  was  neutral.  In  order  to  establish  the  solubility 
of  this  salt,  the  crystals  were  rubbed  down  with  water  of  17°, 
and  then  some  time  shaken.  The  perfectly  saturated  solution  was 
afterwards  filtered,  43.1  grms.  of  the  filtrate  were  evaporated  to 
dryness,  and  the  residue  dried  at  110°,  the  result  was  0.325  grms. 
of  sulphate  of  quinidine.  It  required,  therefore,  130  parts  of 
water  at  17°  to  dissolve  one  part  of  the  sulphate. 
33.5  grms,  of  a  solution  saturated  at  100°,  yielded,  after  being 
evaporated  and  dried  at  100°,  1.904  grms.  of  the  salt  ==  one 
part  of  the  salt  in  16  parts  of  water.  Sulphate  of  quinidine  dis- 
solves very  readily  in  alcohol,  but  is  almost  insoluble  in  ether. 
Analysis  of  100  parts  : 
Found. 
i.         ii.         in.         iv.        Average.  Calculated. 
Carbon,    .    .   64.70    64.79       —         —          64.75  65.25 
Hydrogen,    .     7.18      6.91       —         —            7.05  6.95 
Sulphuric  acid,    —       —      11.99      12.02        12.01  12.08 
Corresponding  formula  :  C36  H22  N2  02   S03  HO. 
Acid  Sulphate  of  Quinidine. — The  salt  was  obtained  by 
adding  to  the  neutral  sulphate  as  much  acid  as  it  already  con- 
tained 
