COMBINATION  OF  GLYCERINE  WITH  ACIDS. 
357 
announced  that  the  base  is  abundantly  contained  in  the  Quin- 
quina cordifolia  of  New  Grenada,  Bolivia  and  Peru. 
These  chemists  are  not  agreed  in  the  composition  and  proper- 
ties of  the  quinidine,  and  no  one  of  them  states  the  proportions 
between  the  quinine  and  quinidine  contained  in  the  suspected 
barks. 
The  most  striking  characteristics  of  the  quinidine  appear  to 
be  its  constant  crystallization,  its  very  slight  solubility  in  ether, 
the  greater  solubility  of  its  sulphate  in  water,  compared  with 
that  of  the  sulphate  of  quinine. 
MM.  Bouquet  and  Schauffele  have  examined  a  New  Grenada 
Quinquina  imported  largely  into  Europe  ;  it  comes  from  near 
Fusagasuya,  and  is  known  under  the  name  of  Quinquina  caqueta. 
Twelve  kilogrammes  of  bark  have  afforded  as  pure  quinine  as 
that  extracted  from  the  Q.  calysaya  ;  the  sulphate  has  all  the 
characters  of  the  sulphate  of  quinine,  and  shows  no  trace  of 
quinidine. 
In  the  black  bittern  which  affords  ordinarily  the  quinidine, 
MM.  Bouquet  and  Schauffele  have  found  some  grammes  of  crys- 
tallized products,  resembling  quinidine  in  some  of  their  charac- 
ters, but  too  different  to  be  confounded  with  it.  The  total 
quantity  of  this  crystallized  product  corresponded  to  3  p.  c. 
by  weight  of  the  sulphate  of  quinine  obtained,  in  the  treatment 
of  the  Quinquina  essayed.  It  is  easily  understood  that  the 
works  of  a  large  manufacturer  might  produce  these  crystallized 
matters  in  small  specimens,  but  not  for  adulterating  the  sulphate 
of  quinine. 
These  authors  conclude  that  the  properties  of  the  quinidine 
are  so  uncertain  that  it  is  prudent  to  wait  for  more  investigation 
before  admitting  it  among  ascertained  chemical  bases  Ameri- 
can Journal  of  Science  and  Arts,  March,  1853. 
ON  THE  COMBINATION  OF  GLYCERINE  WITH  ACIDS. 
By  M.  Berthelot. 
According  to  the  researches  of  M.  Chevreul  on  the  fatty  bodies, 
most  of  the  substances  examined  by  bim  were  capable  of  being  re- 
solved by  saponification  into  fatty  acids  and  glycerine,  with  fixation 
of  the  elements  of  water.    The  analogy  established  by  this  fact 
