^°'  Mar'^'f882!^™"}     PracUcal  Notes  from  Foreign  Journals.  119 
by  acidulous  drinks.  Chinoline  tartrate  seems  to  deserve  the  prefer- 
ence of  all  known  compounds  of  the  alkaloid,  the  solubility  being 
intermediate  between  the  deliquescent  compounds  with  mineral  acids, 
and  the  sparingly  soluble  ones  with  the  aromatic  acids. — Phar.  Ztg., 
1882,  No.  2. 
Large  Dose  of  Chloi^al  Hydrate. — Contrary  to  the  physician^s  direc- 
tions, a  man  suffering  from  delirium  tremens  took  in  about  half  an 
hour  15  grams  of  chloral  hydrate  without  any  ill  effects.  The  editor 
of  Pharm.  Zeitung"  (1881,  No.  98)  directs  attention  to  a  case  which 
occurred  in  Elberfeld  in  1874,  and  in  which  the  same  dose,  15  grams, 
produced  death.  The  maximum  dose  of  chloral  hydrate  is,  in  Ger- 
many, assumed  to  be  3  to  4  grams,  and  in  a  day  8  grams. 
Toxic  Effects  of  Monobromated  Camphor  were  observed  by  Prof.  M. 
Rosenthal,  1  gram  being  taken  in  one  case  and  in  another  3  grams, 
the  patient  remaining  unconscious  for  six  hours,  recovering  conscious- 
ness only  after  violent  vomiting.  The  treatment  recommended  con- 
sists in  giving  an  emetic,  afterwards  acetic  ether,  coffee  with  rum,  and 
in  case  of  a  considerable  reduction  of  the  temperature  of  the  body,  in 
friction  with  warm  clothes,  etc. — Phar.  Ztg.,  1881,  No.  94. 
Compound  of  Strychnine  idth  Iodoform. — According  to  Lextrait  such 
a  compound  may  be  obtained  when  5  grams  of  crystallized  iodoform 
and  12  grams  of  strychnine  are  dissolved  in  about  500  cubic  centime- 
ters of  85  per  cent,  alcohol  at  a  temperature  approaching  the  boiling 
point.  After  24  hours  crystals  separate  from  this  solution,  which  are 
washed  with  a  little  alcohol,  quickly  pressed  between  bibilous  paper, 
and  dried  with  exclusion  of  the  light  and  air.  The  compound  has 
the  composition  (C2iH22N202)3CHl3.  It  is  decomposed  by  light  with 
the  separation  of  iodoform.  It  is  insoluble  in  both  hot  and  cold 
water ;  alcohol  of  98  per  cent,  dissolves  3*40  grams  in  a  liter  at 
15°C. ;  in  ether  and  chloroform  it  is  likewise  soluble.  On  being 
heated  to  90°C.,  it  begins  to  decompose,  and  chars  at  130°C.  With 
boiling  water  it  is  decomposed  with  the  volatilization  of  iodoform, 
while  stychnine  remains ;  the  alcoholic  solution  suffers  a  partial  disso- 
ciation, so  that  it  is  easy  to  purify  the  compound  by  repeated  crystalli- 
zation from  alcohol  without  a  large  portion  becoming  decomposed. 
With  quinine  iodoform  appears  to  form  a  similar  compound.  —  Pharm. 
Zeitung,  No.  94  from  Journ.  Pharm.  Chem. 
A  Correctant  of  the  Odor  of  Iodoform. — Otto  Ruetz  finds  the  substance 
best  adapted  for  diminishing  or  concealing  the  disagreeable  odor  of 
