Am.. Tour.  Pharm.  | 
Mar.,  1882.  / 
Sjjrupus  Fei^ri  Protochloiddi. 
129 
SYRUPUS  FERRI  PROTOCHLORIDI. 
Editor  Amer.  Journal  of  Pharmacy: 
The  fact  of  sugar  reducing  the  ferric  to  ferrous  chloride  in  the  rays 
of  the  sun  induced  me  to  prepare  a  syrup  of  protochloi'ide  of  iron, 
which  in  every  respect  is  superior  and  preferable  to  the  tincture  of 
chloride  of  iron  and  which,  if  adopted  into  the  U.  S.  Pharmacopoeia,  will 
no  doubt  in  most  cases  take  the  place  of  the  tincture,  being  agreeable  to 
taste,  not  corroding  or  blackening  teeth,  and  more  easily  assimilated  by 
the  blood. 
The  following  is  the  formula  adopted  by  me : 
R    Liq.  ferri  perchloridi,  U.  S.  P.,       .         .         .  f^vj  n|xx 
Glyceriiii,    .  .         .    '  .         .         ,         .  ^iv 
Syr.  simpl.,  q.  s.  ad  .  .  '  .  Oi 
Olei  rosae,  olei  neroli,       .  .         .         .       aa  gtti 
Mix  and  expose  to  the  sun  until  entirely  colorless. 
Three  or  four  days  will  be  sufficient  in  summer,  six  to  eight  in  very 
cold  weather,  the  coldest  weather  not  being  an  impediment  for  the 
reduction,  which  can  be  promoted  by  heating  the  syru^)  near  the  stove 
before  exposing  it  to  the  sun. 
In  iron  strength  1  fluidraclim  of  this  syrup  is  equal  to  10  minims 
of  tinctura  ferri  chloridi. 
This  syrup  has  become  quite  a  favorite  with  several  physicians  in 
this  place,  being  especially  suitable  for  children,  and  I  think  it  deserves 
to  be  regarded  as  one  of  the  most  agreeable  and  active  iron  prepara- 
tions. It  can  be  mixed  without  change  of  color  or  decomposition  with 
elixir  of  calisaya  bark,  tincture  gentian,  the  syrup  and  elixir  of 
hypophosphites,  solution  of  bromides,  etc. 
In  diffused  daylight  it  will  acquire  a  brownish  color  without  chang- 
ing its  qualities ;  a  separation  of  grape  sugar  has  not  been  noticed,  on 
keeping.  Alfred  Fruh. 
Greenville,  N.  J.,  Feb.  9. 
Note. — Syrup  of  ferrous  chloride  is  made  in  France  by  dissolving 
5  grams  of  dry  ferrous  cliloride  in  20  grams  of  orange  flower  water 
and  adding  800  grams  of  simple  syrup  and  175  grams  of  syrup  of 
orange  flower.    See  this  journal,  1877,  p.  349.  Editor. 
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