A™jJf^'--^gharm.j         ^^^g      ^/^g  Cinchonci  Alkaloids.  361 
bohedral  prisms.  •  When  gently  heated  in  a  vacuum  it  sublimes  simi- 
larly to  sal  ammoniac. 
The  acid  tartrate  of  conicine  is  obtained  by  the  combination  of  the 
calculated  amount  of  base  and  acid ;  by  the  spontaneous  evaporation 
of  its  solution  it  forms  right  rhombohedral  prisms,  containing  two 
molecules  of  water  of  crystallization. 
The  neutral  oxalate  of  conicine  forms  indeterminable  crystals,  in 
mamillated  groups,  and  contains  no  water  of  crystallization. 
The  author  has  also  obtained  a  borate,  carbonate  and  picrate  of  coni- 
cine, and  double  salts  with  sulphate  of  aluminium  and  chloride  of  zinc, 
but  these  compounds  have  not  been  analyzed. — Ibid.,  pp.  526  to  528, 
from  Ibid.,  14,  p.  1765. 
NOTE  ON  THE  CINCHONA  ALKALOIDS. 
By  O.  Hesse. 
About  the  middle  of  March  in  last  year  I  discovered  in  the  mother 
liquor  of  homocinchonidine  sulphate  a  new  alkaloid  which  presents 
several  points  of  resemblance  to  homocinchonidine  as  well  as  to  cin- 
chonidine,  but  differs  from  both  those  alkaloids,  especially  in  its 
behavior  towards  potassium  permanganate  in  acid  solution  Pharm- 
Jour."  [3],  vol.  xii,  p.  179).  In  consequence  of  a  communication  from 
Forst  and  Bohringer  ("Berichte,"  xiv,  1270),  I  subsequently  reported 
upon  this  investigation  and  indicated  that  the  hydrocinchonidine  of 
Forst  and  Bohringer  was  probably  identical  with  my  alkaloid  and  that 
it  might  exist  in  the  cinchonidine  described  by  those  chemists  as  chem- 
ically pure  (^^Berichte,"  xiv,  1685). 
The  investigation  in  this  direction  of  actually  pure  cinchonidine, 
afterwards  undertaken  by  me,  gave  not  the  least  trace  of  hydrocin- 
chonidine, whilst  commercial  cinchonidine  from  different  sources  yielded 
it  in  varying  quantities,  and  further  showed  that,  in  respect  to  its 
properties,  hydrocinchonidine  agreed  perfectly  with  the  alkaloid  to 
which  I  had  given  the  name  "cinchamidine  "  {"  Berichte,''  xiv,  1893 
The  only  remaining  distinction  between  hydrocinchonidine  and  cin- 
chamidine  was  therefore  to  be  sought  in  the  respective  formulje,  CjgHa^ 
NjO  and  C20H26N2O2.  This  difference  may,  however,  be  of  no 
importance,  as  I  have  been  informed  on  good  authority  that  the  hydro- 
cinchonidine was  not  analyzed,  but  in  assigning  to  it  a  formula  they 
were  guided  by  other  considerations. 
