426 
Varieties. 
J  Am.  Jour.  Pharm. 
I    August,  1882. 
the  gastric  mucous  uiembrane.  Second.  Poisoning  occurs  certainly  where 
the  acid  has  been  applied  to  the  skin  or  injected  into  a  serous  or  mucous  or 
abscess  cavity.  From  tlie  exposed  surface  of  a  wound  the  absori)tion  is 
very  slight,  and  the  toxic  effects  trifling.  The  mucous  membrane  of  the 
resijiratory  passages  may  serve  as  tlie  phice  of  introduction  of  the  poison. 
Third.  The  effects  may  assume  a  very  acute  form,  a  less  acute  form,  or  a 
chronic  form.  Fourth.  There  exist  certain  idiosyncrasies ;  women  and 
children  are  especially  liable  to  carbolic  acid  poisoning.  Fifth.  The  toxic 
dose  is  variable.  In  persons  predisposed,  one  grain  of  carbolic  acid  may 
be  sufffcient  to  poison.  Sixth.  Carbolic  acid  as  an  api^lication  to  contused 
wounds  should  be  used  with  caution,  and  in  some  cases  should  even  be 
suhstituted  by  a  less  dangerous  agent.  Seventh.  The  treatment  of  severe 
carbolic  acid  poisoning  should  consist  in  artificial  respiration,  diffusible 
stimulants,  especially  the  hypodermic  injection  of  ether.  In  other  cases- 
the  removal  of  the  cause,  through  the  discontinuance  of  the  remedy,  will 
suffice  to  remove  the  symptoms. — Chic.  Med.  Review^  June  1. 
An  Anti-Nauseant.— R  Creasote,  20  drops;  acet.  acid,  40  drops;, 
morph.  sulph.,  '1  grains;  water,  2  ounces,  M.  Sig.  Teaspoonful  in  a 
little  water.— OAio  Med.  Jour.,  April,  1882. 
The  Eenzoates  in  Dysentery.— Surgeon  Harris  ("Ind.  Med.  Gaz.") 
states  that  fifteen  grains  of  benzoate  of  ammonium  or  sodium,  three  or  four 
times  a  day,  are  of  the  utmost  value  in  treatment  of  acute  and  sub-acute 
disentery.  This  drug,  more  especially  the  ammonium  salt,  causes  an  active 
secretion  of  bile  from  the  liver  with  cessation  of  the  acute  symptoms.  In 
the  majority  of  cases  the  patients  readily  tolerate  the  drug;  underwits  use 
the  stools  rapidly  become  fecal,  possibly  owing  to  the  excessive  secretion  of 
bile,  which  is  thus  poured  into  the  intestine,  and  acts  beneficially  on  the 
congested  and  iierhaps  ulcerated  large  iwii^^i'nM^.— Practitioner ,  Feb. 
HoMATROPiN  IN  THE  TREATMENT  OF  PHTHISIS.— Dr.  Froumiiller 
reports  (  "  Memorabilien  ")  sixteen  cases  of  phthisis  with  night-sweats  in 
which  homatropin  was  successfully  used.  The  usual  dose  was  '15  (gr.iiss) 
in  pill  form,  or  -015  (gr.V)  by  injection.  It  was  found  that  one  injection 
would,  as  a  rule,  stop  the  night-sweats  for  several  days.  The  fever  and 
cough  were  also  lessened,  and  the  drug  seemed  to  have  the  effect  of  bringing 
the  disease  to  a  stand-still  for  a  time.  The  advantage  over  atropin  is  tliat 
it  (homatropin)  produces  its  effects  without  any  toxic  symptoms,  such  as 
