REMARKS  ON  PROPYLAMINE 
111 
It  should  then  be  set  aside  to  crystallize.  In  a  few  hours  it  be- 
comes nearly  or  quite  solid.  If  necessary,  the  crystals  may  be 
thrown  upon  a  funnel,  and  allowed  to  drain,  and  finally  laid  upon 
bibulous  paper.  As  thus  prepared,  they  are  perfectly  snow-white, 
perfectly  dry,  and  not  deliquescent.  Some  specimens  exposed  to 
the  air  for  several  days  appeared  to  effloresce. 
Philadelphia,  1st  mo.  16,  1860. 
REMARKS  ON  PROPYLAMINE 
By  Dr.  R.  H.  Stabler. 
Esteemed  Friend,  Wm.  Procter,  Jr.: 
In  the  number  of  the  Journal  for  "  March,"  1859,  the  process 
for  preparing  Propylamin  was  published,  together  with  the  ex- 
perience of  Dr.  Awenarius  of  St.  Petersburg,  as  to  its  use  in 
acute  and  chronic  rheumatism,  which  appeared  so  well  sup- 
ported by  well  conducted  clinical  experiments  as  to  entitle  the 
remedy  to  a  trial  in  this  hitherto  unmanageable  disease. 
I  prepared  a  portion  of  it  from  herring  pickle  soon  after 
reading  the  article,  and  induced  some  of  our  physicians  to  use  it 
in  their  practice,  which  resulted  in  establishing  its  reputation 
amongst  us  as  an  indispensable  remedy.  It  has  been  in  use 
here  about  nine  months,  and  has  been  administered  in  about 
fifty  cases  with  most  marked  effect,  seldom  failing  to  give  relief 
in  twenty-four  or  thirty-six  hours  in  acute  cases,  and  a  longer 
time  in  chronic  rheumatism.  I  think  its  great  value  is  demon- 
strated in  acute  rheumatism  of  young  subjects,  where  the  dis- 
ease, unless  quickly  controlled,  is  so  liable  to  attack  the  struc- 
tures of  the  heart.  One  case  of  the  kind  presented  in  the  prac- 
tice of  Dr.  I.  J.  Murphy  of  this  place,  in  a  little  boy ;  com- 
mencing with  swelling  of  the  knees,  ancles  and  other  joints,  high 
fever,  full,  bounding  pulse,  and  other  symptoms  promising  a 
long,  tedious  case  under  the  usual  modes  of  treatment ;  he  was 
directed  to  take  the  propylamin  in  the  usual  doses,  [2  or  3 
drops  in  water  for  an  adult,]  and  was  convalescent  in  three  davs. 
Another  physician  told  me  a  few  days  ago  he  had  used  it  with 
much  satisfaction  and  uniform  success. 
A  good  deal  has  been  published  on  the  preparation  and  ad- 
ministration of  the  remedy  in  the  Journal  and  other  periodicals, 
i 
