PRODUCTS  OF  THE  FERMENTATION  OF  MUCIC  ACID.  33-5 
stration  of  strength,  nor  stupor;  but  in  large  doses,  and  from  a 
constipated  state  of  the  bowels,  it  is  liable  to  produce  nausea, 
which  in  the  former  case  may  be  relieved  by  a  small  dose  of 
sal  volatile,  and  in  the  latter,  by  recourse  to  aperients. 
Therapeutic  Effects. — The  changes  produced  by  this  pre- 
paration on  the  system  are — first,  a  gentle  heat  at  the  stomach, 
followed  by  a  general  glow  and  total  absence  of  pain  ;  second, 
a  calm  and  refreshing  sleep ;  and  third,  an  increase  in  the 
pulse  from  a  "  small,  weak,  thready,  hurried,  or  bounding  one, 
to  a  full,  yielding,  elastic,  natural  sort  of  one,  decreasing  in  fre- 
quency of  beats,  as  well  as  resistance,  to  a  healthy  condition." 
Of  it  powers  in  the  cure  of  consumption  Dr.  Stonehouse  re- 
marks : — "  The  cases  (among  others)  in  which  I  have  employed 
it  have  been  twelve  cases  of  phthisis  ;  eight  of  these  patients  had 
been  examined  by  other  medical  men,  and  had  been  regarded  as 
genuine  cases  of  consumption,  so  that  the  nature  of  the  disease 
does  not  rest  upon  my  testimony  alone.  They  were  all  well- 
marked  cases;  for  I  do  not  mention  several  others  in  an  incipient 
stage.  Two  of  the  cases  were  in  the  last  stage — i.e.,  cavities  had 
formed  in  the  lungs  ;  two  others  were  bordering  upon  this  stage. 
The  remaining  eight  were  in  the  second  stage,  that  of  softening  ; 
in  five,  of  these  haemoptysis  was  a  prominent  symptom.  All 
these  cases  have  done  or  are  doing  exceeding  well.  Five  of  them 
have  quite  recovered;  the  others,  with  one  exception,  are  in  a 
fair  way  towards  recovery. 
Doses — The  dose  of  this  preparation  must  be  regulated  ac- 
cording to  the  nature  of  the  complaint.  As  an  anodyne  for  fe- 
brile, inflammatory,  or  neuralgic  affections  the  dose  is  from  ten  to 
thirty  drops;  diaphoretic  in  cases  of  coughs,  colds,&c,  ten  to  twen- 
ty drops  ;  sedative  in  consumption,  &c,  twenty  to  fifty  drops  ;  an- 
tispasmodic in  gout,  rheumatism,  &c,  twenty  to  forty  drops  ; 
astringent  in  cholera,  diarrhoea,  &c,  fifty  to  one  hundred  drops. 
It  is  best  administered  on  lump  sugar,  and  given  at  intervals 
from  every  half  hour  to  every  four  hours.-—  Chemist  and  Drug- 
gist, Feb.  15th,  1860. 
