88 
Ash  of  Cinchona  Bark. 
Am.  Jour.  Phartn. 
teb.,  1887. 
C.  officiTicili'S. 
Insoluble  silica 
5.75 
n  fiO 
Soluble  silica 
1.42 
4  40 
Alnminfl  • 
lilUlilllld          •                .  . 
9  70 
4  94 
3  91 
TVTn  ti  era  n  prp 
.      •  trace 
Lime 
32.70 
32.80 
Magnesia  .... 
2.07 
2.52 
Potash  ..... 
16.35 
12.49 
Soda  .... 
3.40 
2.28 
f^ta  Thorn  p  fipirl 
27.22 
97  77 
Sulphuric  acid 
1.16 
1.08 
Phosphoric  acid 
3.93 
3.19 
Chlorine  .... 
.45 
.42 
100.00 
100.00 
The  chief  constituent  is  the  lime  which  forms  nearly  one-third  of 
the  whole,  and  exists  in  the  ash  in  the  form  of  carbonate.  The  next 
element  of  importance  is  the  potash,  which  amounts  to  one-sixth  and 
one-eighth  of  the  whole  ash  respectively. 
About  fourteen  years  ago  P.  Carles  wrote  a  paper  on  the  "Com- 
plete Analysis  of  Cinchona  Barks,"  in  the  Repertoire  de  Pharmacie 
(new  series),  vol.  i.,  p.  60  (which  appeared  in  the  Pharmaceutical 
Journal,  March  15,  1873),  and  a  complete  analysis  is  given  of  the 
ash  of  Huanuco,  calisaya  and  succirubra  barks  from  South  America. 
His  examinations  agree  on  the  whole  with  the  above,  but  he  finds 
traces  of  copper  and  appreciable  quantities  of  manganese  present. 
Although  there  was  quartz  present  in  most  of  my  samples,  weighed 
as  insoluble  silica,  yet  there  was  no  trace  of  copper;  and  the  absence 
of  more  than  traces  of  manganese  is  in  accordance  with  the  nature  of 
the  ft  ilgiri  soils.  I  am  confirming  Carles  in  showing  what  a  small 
quantity  of  chlorine  is  present.  As  to  bark  rich  in  quinine  asso- 
ciated with  abundance  of  lime  salts,  I  cannot  agree  that  there  is  any 
relation  between  the  alkaloids  and  the  mineral  elements.  The  cin- 
chonas of  South  America  were  poorer  in  quinine  then  than  the  In- 
dian barks  are  now,  and  they  yielded  about  half  the  amount  of  ash. 
On  the  other  hand  the  Ledger  barks,  which  are  richer  in  quinine 
than  succirubras,  always  contain  less  ash,  and  consequently  a  less 
amount  of  lime.  There  is  not  much  lime  in  the  Nilgiri  soil,  yet  it 
seems  an  essential  ingredient  in  cinchona  bark,  and  is  taken  up  in 
large  quantities,  whether  the  cinchona  is  grown  in  India  or  America. 
