A.m.  Jour.  Pharm. 
564        Pharmaceutical  Notes  on  New  Compounds.  {Am'^ov 
tageously  prescribed  in  the  form  of  powders  containing  the  above-men- 
tioned dose,  since  from  its  tastelessness  it  is  readily  taken  by  patients.  « 
Amylene  hydrate. — Tertiary  amylic  alcohol,  dimethyl  ethylcarbinol, 
^3>  C.OH. 
C2H5/ 
Only  a  few  weeks  ago  this  compound  was  recommended  by  Pro- 
fessor Jolly  and  von  Mering  as  a  soporific,  in  which  class  of  remedies 
it  appears  to  have  taken  a  prominent  place.  Before  applying  it  to 
patients,  numerous  experiments  on  animals  had  been  carefully  carried 
out.  A  dose  of  5j.  is  sufficient  to  produce  sleep  for  six  or  eight  hours. 
No  unpleasant  secondary  effects  are  recorded. 
The  remedy  is  given  in  water  (in  which  it  is  soluble  in  the  propor- 
tion of  1  : 1 2)  with  a  little  juice  of  liquorice. 
Amylene  hydrate. 
Liq.  glycyrrhizae  aa  gj. 
Aq  ad  gj. 
Sig.— To  be  shaken  before  use. 
It  is  also  administered  in  capsules  of  gelatin. 
It  is  a  clear  fluid  with  an  odor  reminding  one  slightly  of  camphor ; 
it  is  soluble  also  in  alcohol.  Specific  gravity  0*812  at  53'6°  F.  Boil- 
ing point  216°  F. 
Antifebrin,  acetanilide,  phenylacetamide,  C6H5NH.CH3CO. 
Since  the  first  experiments  with  this  valuable  remedy,  performed  by 
Drs.  Calm  and  Hepp,  in  Strasburg,  antifebrin  has  been  carefully 
studied  by  others,  and  with  the  same  satisfactory  results.  It  possesses 
the  advantages  over  other  remedies  of  this  class  of  being  low  in  price, 
and  moreover  the  dose  is  small ;  2  to  10  grains  once,  twice,  or,  at  most, 
three  times  a  day  sufficing  to  produce  a  considerable  reduction  of  tem- 
perature in  cases  of  typhoid  fever,  pneumonia,  also  in  erysipelas  and 
acute  rheumatic  gout.  It  is  given  in  powders  as  well  as  in  solution  ; 
for  the  latter  mode  of  administration  it  will  be  found  most  advisable 
to  dissolve  it  in  brandy,  subsequently  adding  a  little  water  and  syrup. 
The  following  formula  is  given  as  an  example : — 
Antifebrin   gj. 
Brandy   §ivss. 
Dissolve  and  add — 
Distilled  water, 
Simple  syrup  of  each  gvj. 
One  tablespoon ful  to  be  taken  as  directed. 
