I 
186 PHARMACEUTICAL NOTICES. 
ether soon spoils, and undergoes the acetous fermentation, 
while, if that ethereal spirit is added, it keeps for a considera- 
ble time. 
Coxe's Hive Syrup. 
A formula and process for making this preparation, was 
published in the 11th volume of this Journal, (page 198,) 
which was believed at the time of its publication to have ar- 
rived at complete success, so far as related to obtaining an ac- 
tive remedy, which would keep during warm weather, with- 
out undergoing fermentation. 
The process alluded to, consists in treating the senega and 
squill with diluted alcohol, in a displacement apparatus, 
until twice the quantity of fluid is obtained that is required 
to make the preparation ; then raising the temperature to the 
boiling point, to coagulate the albumen, then evaporating to 
one-half, and straining carefully, in order that all the coagu- 
lated albumen may be removed. Lastly,adding two pounds, 
avoirdupois, of loaf sugar to each pint of the clear infusion. 
This process, with some modifications, is the one recommend- 
ed in the Report of the Committee of Revision on the U. S. 
Pharmacopoeia. Those that have employed this formula? 
have been much pleased with it for the following reasons: — 
Firstly, The product is decidedly more active than that of 
the Pharmacopoeia of 1830. Secondly, It is much less liable to 
ferment. Thirdly, Being made with sugar instead of honey, it 
is a more handsome preparation. 
Coxe's Hive Syrup, made as above, was found to keep very 
well during the past summer, except on a few of the warmest 
days, when it evinced a slight disposition toward fermentation, 
at a temperature of from 80 to 90° Fahr., but not more than 
simple syrup, kept under the same circumstances. To total- 
ly prevent this, it is proposed to add two fluid drachms of Hoff- 
man's anodyne to each pint of the syrup, for summer use; 
which, without at all injuring its qualities as a remedy, will 
effectually preserve it from fermentation. 
A process, (said to be that originally employed by Dr. 
