PHARMACEUTICAL NOTICES. 
187 
Coxe,) has been lately used by several apothecaries, — which 
is the following. Proceed in the way above stated, to pre- 
pare the infusion or tincture of seneka and squill, then 
evaporate to the consistence of a syrup, and mix it with as 
much honey as equals in measure the quantity of the prepara- 
tion required. Lastly, boil gently, to thoroughly mix them, 
and add the tartar emetic. When thus made, Coxe's Hive 
Syrup, it is said, never ferments. 
The objections to its being made by this formula, are, that 
the long evaporation required to reduce five or six pints of 
fluid down to three or four ounces, will tend to injure the ac- 
tivity of the remedy, even when carefully executed; but care- 
less manipulation will certainly produce this effect; and that 
honey varies so much in quality and density as would give 
an irregular consistence to the preparation. 
A specimen of syrup made very carefully by this formula, 
and one made with sugar by the foregoing, without the ad- 
dition of the Hoffman's anodyne, were kept in similar vessels, 
equally exposed to the action of the atmosphere for six weeks, 
and occasionally agitated. 
The latter showed evident signs of fermentation at the end 
of that period, while the former was perfectly unaltered. 
That, prepared with sugar, however, remained perfectly un- 
changed, during the same time, by the presence of the quanti- 
ty of Hoffman's anodyne above indicated. 
Syrups. 
The employment of the Saccharomeler, or instrument for 
measuring the density of syrups, is by no means general. 
Those who are in the habit of employing this useful instru- 
ment in syrup-making, can appreciate the advantages which 
result from its use, both as regards facility of manipulation 
and uniformity of consistence in the preparation. The instru- 
ment is too well known to need a description, but it may be 
well to mention, that as a general rule syrups should be con- 
centrated till they mark 30 degrees on the scale, while boil- 
