ON HYDRATED FEROYIDE OP IRON, ETC. 
243 
of Edinburgh, concerning them. " With respect to the former 
it may be observed, that he appears uniformly to have used 
too small quantities of the oxide, and the experiments of the 
latter hardly seem to have been made with sufficient care, as 
appears in one instance, at least, from his having injected 
both poison and antidote into the lungs, instead of the stomach 
of the rabbit.* 
III. Its Efficacy as an Antidote on Man. In referring 
to these, I must be brief, indicating merely the leading points 
worthy of notice. 
1. The first case on record is probably that of M. Leger. 
A child eighteen months old, drank a solution of fly poison, 
(probably a variable combination of black oxide of arsenic 
and oxide of cobalt,) and was immediately seized with symp- 
toms of violent colic. The accident was soon discovered, and 
the hydrated peroxide was instantly given. Its effects were 
completely successful within a few hours. American Journal 
of the Medical Sciences, vol. xvi. p. 239. 
2. M. Geoffroy, of Paris, gave it in twenty minutes after 
arsenic, stirred about in water, had been swallowed by a man 
aged 36. Four or five pints of water, charged with it, were 
given in a quarter of an hour. Vomiting ensued ; but the 
patient suffered none of the ordinary symptoms of arsenic. 
He had taken a drachm and a half of arsenic. The next 
morning he was well- British and Foreign Medical Re- 
vieiv, vol. i. p. 572. American Journ. Med. Sci., February, 
1836, p. 501. 
3. Drs. Bineau and Majeste of Saumur, in France, related 
* On the action of the Hydrated Sesquioxide of Iron on Arsenic, by Doug- 
lass Maclagan, M. D., Lecturer on Materia Medica. Edinburg Medical 
and Surgical Sournal, volume liv. page 106. This is a valuable paper in 
reference to the chemical action of these substances on each other. I 
have only space to notice the conclusion to which he arrives, and which, 
is, that " the hydrated oxide of iron is a real chemical antidote to arseni- 
oue acid, and that when it removes arsenic from solution and soluble com. 
binations, it acts by chemically uniting with it." The large quantities 
which have been found necessary, are required, not to protect the stomach 
mechanically, but to render the poison chemically inert. 
