1 1 8  Approved  Proprietary  Preparations, 
A.m.  Jour.  Pharm. 
March,  1907. 
be  decomposed  in  the  body.  It  is  a  local  anesthetic  with  an  action 
weaker  than  that  of  cocaine,  but  sufficient  to  prevent  vomiting  from 
gastric  irritation.  Its  antiseptic  action  is  said  to  be  fifteen  times  as 
strong  as  that  of  boric  acid.  It  acts  on  the  central  nervous  system 
similarly  to  chloral,  and  although  the  claim  has  been  made  that 
hypnotic  doses  are  without  effect  on  the  circulation  and  respiration* 
independent  observers  have  described  a  fall  of  blood  pressure  and 
interference  with  respiration  in  animals,  and  consider  it  fully  as 
dangerous  as  chloral.  In  man  lOO  grains  caused  severe  symptoms, 
but  recovery  occurred.  It  is  claimed  that  no  habit  is  induced,  but 
this  may  be  referable  to  its  restricted  employment.  It  is  recom- 
mended as  a  mild  local  anesthetic,  in  dentistry,  etc.,  as  a  preserva- 
tive for  hypodermic  solutions,  for  insomnia,  vomiting  and  for  spas- 
modic conditions.  It  is  also  said  to  be  useful  as  introductory  to 
general  anesthesia,  lessening  excitement  and  nausea.  Dosage. — 
The  dose  is  from  0-3  to  1-5  gramme  (5  to  20  grains)  dry  or  in  cap- 
sules. Hypodermically  as  a  local  anesthetic  a  saturated  aqueous 
solution  may  be  used. 
CHLORETONE. 
A  name  applied  to  chlorbutanol,  which  see.  Manufactured  by 
Parke,  Davis  &  Co.,  Detroit,  Mich. 
CHLORETONE  INHALANT. 
A  solution  of  chloretone,  camphor,  menthol  and  oil  of  cinnamon 
in  liquid  petrolatum. 
Actions  and  Uses. — An  anodyne,  antiseptic,  and  emolient  solution 
for  use  by  inhalation  as  a  very  fine  spray  or  nebula.  Manufactured 
by  Parke,  Davis  &  Co.,  Detroit,  Mich.  s 
CITARIN. 
CH2COONa 
I  CH2 
/  X 
Citarin,  CO  O  =  Na2C7H607,  the  normal  sodium  salt  of 
CH2COONa 
anhydromethylene-citric  acid. 
Actions  and  Uses. — This  is  one  of  the  compounds  which  it  is 
claimed  increase  the  elimination  of  uric  acid  by  forming  very  soluble 
