i8o  American  Medical  Association.  {AmAP°rlir;i907arm' 
oxidizing  and  germicidal  action.  In  consequence  of  this  change, 
these  compounds  are  thought  to  be  particularly  adapted  for  internal 
administration.  The  germicidal  and  antiseptic  properties  of  this 
substance  have  been  attested  by  the  experimental  results  of  several 
observers.  It  has  been  used  in  ophthalmic,  aural  and  nasal  practice 
with  asserted  good  effects  as  an  antiseptic.  It  has  also  been  applied 
internally,  especially  in  typhoid  fever,  with  a  view  to  the  disinfection 
of  the  intestinal  canal,  and  appears  to  be  an  intestinal  antiseptic. 
Dosage. — Acetozone  is  generally  employed  in  aqueous  solution  pre- 
pared  as  follows :  Add  acetozone  to  warm  water  in  the  proportion 
of  I  gramme  to  iooo  c.c.  (15  grains  to  the  quart),  shake  vigorously  for 
five  minutes,  and  allow  to  stand  for  about  two  hours.  Decant  the 
liquid  as  required.  This  solution  may  be  drunk  ad  libitum,  two 
quarts  or  more  being  taken  by  an  adult  in  twenty-four  hours.  Ace. 
tozone  is  also  used  in  oily  solution  as  an  inhalant.  Manufactured 
by  Parke,  Davis  &  Co.,  Detroit,  Mich. 
ADNEPHRIN  SOLUTION. 
A  sterile  solution  of  i-iooo  of  the  suprarenal  active  principle  in 
physiologic  salt  solution  containing  one  half  of  I  per  cent,  of  metha- 
form  (chlorbutanol). 
Actions  and  Uses. — The  actions  and  uses  of  this  preparation  are 
described  under  Suprarenal  Alkaloid.  Dosage. — The  dose  inter- 
nally is  from  o-2  to  2  0  c.c.  (3  to  30  minims)  in  water.  Adnephrin 
is  also  used  in  oily  solution  as  a  spray,  see  Adnephrin  Oil  Spray, 
and  in  the  form  of  ointment,  see  Adnephrin  Emollient.  Prepared 
by  F.  Stearns  &  Co.,  Detroit,  Mich. 
ADRENALIN. 
The  active  alkaloid  of  suprarenal  gland,  prepared  by  the  method 
of  Takamine,  see  Suprarenal  Alkaloid. 
Dosage. — Locally,  1-1000  to  1-15000  solution,  as  the  chloride. 
Internally,  0-3  to  2  c.c.  (5  to  30  minims)  of  I-IOOO  solution.  Hypo- 
dermically,  1  to  15  drops  of  i-iooo  solution,  diluted  with  sterile 
water.    Manufactured  by  Parke,  Davis  &  Co.,  Detroit,  Mich. 
ADRENALIN  CHLORIDE  SOLUTION. 
Dosage. — See  adrenalin.  Prepared  by  Parke,  Davis  &  Co.,  De- 
troit, Mich. 
