AmApOrn;i90T!rm"}       America7i  Medical  Association,  185 
densation  product  of  paraphenetidin  and  acetparaphenetidin  (phe- 
nacetin). 
Actions  and  Uses. — It  is  a  local  anesthetic  like  cocaine,  but  having 
the  advantage  of  quicker  effect  and  an  antiseptic  action.  Five 
minims  of  a  I  per  cent,  solution  when  instilled  into  the  eye  are 
usually  sufficient  to  cause  anesthesia  in  from  1  to  10  minutes.  It  is 
more  toxic  than  cocaine  and  without  effect  on  the  pupil  or  blood- 
vessels. It  is  not  so  useful  as  cocaine  when  the  vasoconstrictor 
effect  of  the  latter  is  desired.  It  is  said  not  to  cause  the  scaliness  of 
the  cornea  which  sometimes  results  after  the  use  of  the  older  remedy. 
Dosage. — It  is  applied  in  a  1  per  cent,  aqueous  solution.  Manufac- 
tured by  Farbwerke,  vorm.  Meister,  Lucius  &  Bruening,  Hoechst  a. 
M.    (Victor  Koechl  &  Co.,  New  York). 
HYPNAL. 
Hypnal,  CUH12N20-CC13CH(0H)2  =  C^H^NX^,  antipyrine 
combined  with  one  molecule  of  hydrated  chloral. 
Actions  and  Uses. — Hypnal  is  an  analgesic  and  hypnotic  resem- 
bling chloral  in  its  action,  but  said  to  be  less  liable  to  produce  in- 
jurious effects  on  the  vaso-motor  centre  of  the  heart.  It  may  be 
used  where  chloral  is  indicated,  as  in  mild  forms  of  mental  excite- 
ment, incipient  delirium  tremens,  and  in  insomnia  caused  by  pain. 
Dosage. — 1  to  2  grammes  (15  to  30  grains);  although  supposed  to 
be  less  toxic  than  chloral,  larger  doses  up  to  3  grammes  (45  grains) 
should  be  used  with  caution.  Manufactured  by  Farbwerke,  vorm. 
Meister,  Lucius  &  Bruening,  Hoechst  a.  M.  (Victor  Koechl  &  Co., 
New  York). 
IODIPIN. 
Iodipin  is  an  iodine  addition  product  of  sesame  oil  containing  10 
per  cent,  iodine,  in  organic  combination. 
Actions  and  Uses. — Iodipin  acts  in  the  system  similar  to  the 
iodides,  being  broken  up  in  a  manner  analogous  to  that  described 
under  bromipin,  which  see.  Its  action  is  more  lasting  and  with  less 
tendency  to  iodism.  Manufactured  by  E.  Merck,  Darmstadt.  (E. 
Merck  &  Co.,  New  York). 
EUMYDRIN. 
Eumydrin  C6H5(HOCH2)  CH-C02-  C7Hn  N(CH3)2NQ3  =  QgH^Og 
N2,  the  nitrate  of  methylated  atropine. 
