Am.  Jour.  Pharm.'j. 
February,  19 17.  ■* 
Carrel-Dakin  Solution. 
3S 
A  25  Cc.  buret  graduated  in  o.i  Cc. 
A  pipet  gaged  for  10  Cc. 
A  decinormal  solution  of  sodium  thiosulphate  (hyposulphite). 
This  decinormal  solution  of  sodium  thiosulphate  can  be  obtained 
in  the  market ;  it  can  also  be  prepared  by  dissolving  25  Gm.  of  pure 
crystalline  sodium  thiosulphate  in  1  liter  of  distilled  water,  and 
verifying  by  the  decoloration  of  an  equal  volume  of  the  decinormal 
solution  of  iodin  by  this  solution.  The  iodin  is  prepared  by  dis- 
solving 1.27  Gm.  iodin  and  5  Gm.  potassium  iodid  in  100  Cc.  of 
water. 
The  material  for  the  dosage  thus  provided,  a  sample  of  the  pro- 
vision of  chlorinated  lime  on  hand  is  taken  up  either  with  a  special 
sound  or  in  small  quantities  from  the  mass  which  then  are  carefully 
mixed. 
Weigh  out  20  gm.  of  this  average  sample,  mix  it  as  completely 
as  possible  with  1  liter  of  ordinary  water,  and  leave  it  in  contact 
for  a  few  hours,  agitating  it  from  time  to  time.  Filter. 
Measure  exactly  with  the  gaged  pipet  10  Cc.  of  the  clear  fluid; 
add  to  it  20  Cc.  of  a  1:10  solution  of  potassium  iodid  and  2  Cc.  of 
acetic  or  hydrochloric  acid.  Drop,  a  drop  at  a  time,  into  this  mix- 
ture a  decinormal  solution  of  sodium  thiosulphate  until  decoloration 
is  complete. 
Quantities  of  Ingredients  for  Ten  Liters  of  Dakin's  Solution. 
Titer  of  Chlorinated 
Lime. 
20 
21 
22 
23 
24 
25 
26 
27 
28 
29 
30 
31 
32 
33 
34 
35 
36 
37 
Chlorinated  Lime, 
Gm. 
230 
220 
210 
200 
192 
I84 
177 
170 
I64 
159 
154 
148 
144 
140 
135 
132 
128 
124 
Anhydrous  Sodium 
Carbonate,  Gm. 
115 
110 
105 
100 
96 
92 
89 
85 
82 
80 
77 
74 
72 
70 
68 
66 
64 
62 
Sodium  Bicarbonate, 
Gm. 
96 
92 
88 
84 
80 
76 
72 
70 
68 
66 
64 
62 
66 
59 
57 
55 
53 
52 
