284 
Advances  in  Pharmacy. 
I  Am.  Jour.  Pharm. 
June,  19 1 7. 
ternally  it  is  used  in  solutions  varying  from  0.5  to  4  per  cent,  in 
strength.  It  can  be  dried  at  or  exposed  to  a  temperature  of  ioo°  to 
1020  C.  without  decomposition  taking  place. 
Toxic  Effect  of  Emetine  Hydrochloride. — Two  American 
Army  physicians  in  a  study  of  140  cases  of  endometric  dysentery 
treated  with  this  drug,  show  that  it  is  well  to  watch  patients  very 
closely  who  are  being  treated  with  emetine.  They  state  that  the 
danger  is  somewhat  similar  to  that  of  salvarsan  in  the  treatment  of 
syphilis.  Two  of  the  patients  died  from  conditions  in  no  way  con- 
nected with  the  disease  for  which  they  were  being  treated,  while  five 
others  showed  unusual  symptoms,  which,  in  the  absence  of  any  other 
known  causes,  were  naturally  attributed  to  the  emetine.  In  the  two 
fatal  cases  there  was  the  inability  to  swallow  water  after  food  had 
reached  the  gullet ;  the  heart  was  rapid  and  uncontrolled ;  there  was 
a  marked  tendency  for  the  head  to  fall  forward,  and  there  was  a 
lobar-pneumonia.  In  the  five  other  cases  the  symptoms  were  similar, 
all  of  which  disappeared  when  the  treatment  ceased  (Military  Sur- 
geon, 40,  58,  1917,  Johnson  &  Murphy). 
Infusion  of  Broom  Tops  as  a  Larvicide. — A  cold  infusion 
made  by  steeping  fresh  crushed  tops  in  water  for  from  ten  to  twelve 
days,  in  a  quantity  sufficient  to  give  to  the  liquor  a  greenish  color, 
was  found  to  be  a  quite  formidable  agent  of  destruction  for  cater- 
pillars. It  was  found  to  be  of  great  benefit  for  watering  cabbage 
as  it  readily  destroyed  the  larvae  of  the  cabbage  butterfly  and  other 
numerous  larvae  which  feed  on  cruciferous  plants.  In  France  it  has 
been  found  to  be  particularly  valuable  for  removing  Cochylis  larvae 
from  vines  and  various  caterpillars  from  apple  trees.  The  infusion 
is  applied  by  simply  spraying  or  watering  over  the  plants  (Rev.  Sci., 
U  Union  pharm.,  through  The  Phar.  J  oar.  &  Pharmacist,  2,  191 7, 
17,  P-  139). 
New  Method  for  Determining  Ozone. — It  is  said  that  the 
following  method  for  determining  the  presence  of  ozone  used  for 
surgical  and  therapeutic  purposes  is  simple,  accurate,  and  sensitive. 
This  determination  depends  on  the  extreme  avidity  of  ferrous  am- 
monium sulphate  for  ozone,  a  reagent  which  is  quite  stable  towards 
ordinary  atmospheric  oxygen  under  the  conditions  of  the  test.  The 
reagent  consists  of  3.92  grams  of  ferrous  ammonium  sulphate v  dis- 
solved in  water  and  20  mils  of  pure  H2S04,  sp.  gr.  1.815,  made  up 
to  one  liter.  This  is  quite  permanent  under  ordinary  conditions. 
Against  this,  a  solution  of  potassium  permanganate,  0.316  gram  is 
