Am.  Jour.  Pharm. 
July,  1 9 17. 
Topical  Applications. 
297 
BOROGLYCERIN. 
Gm. 
$    Boric  acid    620 
Glycerin — a  sufficient  quantity  to  make    1,000 
Heat  nine  hundred  and  twenty  grammes  of  glycerin  in  a  tared 
porcelain  dish  to  a  temperature  between  1500  C.  to  1600  C.  and  add 
the  boric  acid  in  portions,  stirring  constantly  until  all  the  boric  acid 
is  dissolved  and  continue  the  heat  until  the  mixture  has  been  re- 
duced to  1,000  grammes. 
Glycerite  of  Boroglycerin,  60  Per  Cent. 
Gm. 
I£    Boroglycerin    600 
Glycerin — a  sufficient  quantity  to  make    1,000 
Heat  the  boroglycerin  and  600  grammes  of  glycerin  in  a  tared 
porcelain  dish  to  a  temperature  between  1500  C.  to  1600  C,  until 
the  mixture  has  been  reduced  to  1,000  grammes.  When  made  ac- 
cording to  the  above  formula  this  glycerite  of  boroglycerin  has  the 
specific  gravity  of  1.35  at  25 0  C. 
Glycerite  of  Boroglycerin  in  the  Treatment  of  Trachoma,  "Granular 
Conjunctivitis!' 
Trachoma  is  a  disease  of  the  conjunctiva  palpebrarum  charac- 
terized by  infiltration  of  the  follicles,  which  are  distended  by  the 
products  of  the  inflammatory  processes. 
It  is  highly  contagious  and  when  neglected  often  destructive  of 
vision. 
The  writer's  attention  was  called  to  the  promising  action  of 
glycerite  of  boroglycerin  made  according  to  the  old  formulae  and  he 
was  urged  to  attempt  the  task  of  improving  it  by  increasing  its  per- 
centage of  boric  acid  and  rendering  the  product  anhydrous. 
In  the  pursuit  of  these  objects  entirely  new  methods  of  prepar- 
ing glycerite  of  boroglycerin  were  devised,  especially  in  the  applica- 
tion of  heat  and  the  attainment  of  what  heretofore  appeared  to  be 
forbidden  temperatures. 
The  formula  evolved  by  a  long  series  of  experiments  is  herewith 
presented. 
The  product  is  anhydrous  and  contains  60  per  cent,  of  boro- 
glycerin, which  contains  62  per  cent,  of  boric  acid,  and  in  the  hands 
