298 
Topical  Applications. 
Am.  Jour.  Pharm. 
July,  1917. 
of  many  skilled  ophthalmologists  has  proved  of  inestimable  value 
in  the  treatment  of  trachoma,  indeed  frequently  causing  a  com- 
plete recovery  and  without  cicatrices. 
Of  the  formulae  for  the  other  medicaments  it  may  be  said  that  in 
several  instances  the  refinements  in  method  of  compounding  have 
resulted  in  more  perfect,  efficient  and  eligible  preparations. 
Ointment  of  Glycerite  of  Boroglycerin. 
Gm. 
5.    Glycerite  of  borogrycerin    20 
Sodium  borate    2 
Spermaceti    20 
White  wax    20 
Oil  of  sweet  almond    38 
To  the  spermaceti  and  white  wax  which  have  been  melted  add 
the  oil  of  sweet  almond  and  continue  the  heat  to  a  temperature  of 
8o°  C.  To  the  glycerite  of  boroglycerin  add  the  sodium  borate  and 
bring  to  a  temperature  of  1200  C.  and  continue  until  all  of  the 
sodium  borate  has  been  dissolved.  Add  the  mixture  of  the  glycerite 
of  boroglycerin  and  sodium  borate  to  the  oil  mixture  and  stir  rapidly 
and  continuously  until  the  ointment  congeals  and  becomes  of  a  uni- 
form consistence. 
This  ointment  is  very  hygroscopic  and  must  be  placed  immedi- 
ately in  sealed  tin  tubes  or  air-tight  containers. 
Ointment  of  Citrate  of  Copper  in  Glycerite  of  Boroglycerin. 
Gm. 
I£    Citrate  of  copper    8 
Glycerite  of  boroglycerin    80 
Wool  fat   2 
White  petrolatum    10 
Heat  the  glycerite  of  boroglycerin  to  1250  C.  and  slowly  add  the 
citrate  of  copper  and  continue  the  heat  until  all  of  the  citrate  of 
copper  has  been  dissolved.  Remove  the  heat  and  when  the  mixture 
,  has  cooled  to  75 0  C.  add  the  wool  fat  and  white  petrolatum  and  stir 
constantly  until  it  has  cooled  to  500  C.  and  transfer  to  airtight 
containers. 
Copper  citrate  was  brought  to  the  writer's  attention  as  being  a 
most  valuable  agent  in  the  treatment  of  certain  varieties  of  trachoma 
and  of  disturbances  of  the  follicles  of  the  ciliae. 
