AmjIn"ri8P7h8arm'}         Fluid  Extract  of  Cimicifuga.  1 1 
tained  in  the  first  24  fluidounces  of  percolate,  consequently  44  fluid- 
ounces  of  alcohol  were  required  to  extract  112*71  grains  of  extractive 
matter. 
This  operation  I  found  very  tedious  and  troublesome.  As  mentioned 
in  connection  with  experiment  third,  cimicifuga  settles  into  a  tough 
mass  when  worked  in  this  way,  so  compact  as  almost  to  prevent  the 
menstruum  from  passing.  More  than  three  weeks  were  consumed  in 
preparing  this  24  fluidounces  of  fluid  extract.  I  gave  the  experiment 
every  attention  possible  for  me  to  spare  from  other  operations.  I 
stationed  a  boy  part  of  the  time  to  reserve  the  percolates,  and  with  all 
my  care  occasionally  the  surface  of  the  powder  would  become  exposed 
and  crack.  Necessarily,  I  was  compelled  to  suspend  the  operation 
nights  and  upon  the  sabbath. 
TABLE  5. 
Percolate  from  24 
oz.  powdered 
Cimicifuga. 
Dry  extract  contained. 
Extractive  mattercontained  in  16  floz. 
finished  fluid  extract. 
Fluid  ounces. 
Grains. 
Grains. 
16 
805-08 
5 
8 
8976 
8 
55'52 
8 
43-68 
8 
41-36 
8 
40  16 
7 
26  88 
68 
1236-74 
824-46 
When  this  line  of  experiments  was  commenced  I  also  instituted  an 
example  with  simple  percolation,  corresponding  excepting  that  the 
powder  was  placed  in  a  single  percolator.  The  percolate  was  received 
in  similar  portions  ;  table  No.  5  tabulates  the  result.  Comparing  the 
two  operations  I  find  that  simple  percolation  extracted  69*02  grains  of 
extractive  matter  more  than  repercolation.  In  the  first  thirty-six  fluid- 
ounces,  corresponding  with  the  amount  of  percolate  derived  from  24  troy- 
